Evaluation of a multi-endpoint assay in rats, combining the bone-marrow micronucleus test, the Comet assay and the flow-cytometric peripheral blood micronucleus test

Damian E. Bowen, James Whitwell, Lucinda Lillford, +6

Mutation Research/Genetic Toxicology and Environmental Mutagenesis

ThrombopoiesisComet AssayBone Marrow FailureBone-marrow Micronucleus TestMulti-endpoint Assay +9

JaCVAM-organized international validation study of the in vivo rodent alkaline comet assay for detection of genotoxic carcinogens: II. Summary of definitive validation study results

Yoshifumi Uno, Hajime Kojima, Takashi Omori, +25

Mutation Research/Genetic Toxicology and Environmental Mutagenesis

OncologyMedicineGenotoxic CarcinogensPathologyToxicology Testing +5

Critical issues with the in vivo comet assay: A report of the comet assay working group in the 6th International Workshop on Genotoxicity Testing (IWGT)

Günter Speit, Hajime Kojima, Brian Burlinson, +13

Mutation Research/Genetic Toxicology and Environmental Mutagenesis

Critical IssuesVivo CometEnvironmental HealthToxicology TestingToxicology +4

Genotoxicity assessment of the flavouring agent, perillaldehyde

Cheryl A. Hobbs, Sean V. Taylor, Carol Beevers, +5

Food and Chemical Toxicology

Herb PerillaGenotoxicity AssessmentAllergyMedicineToxicology +13

In vivo genotoxicity testing strategies: Report from the 7th International workshop on genotoxicity testing (IWGT)

David Kirkland, Yoshifumi Uno, Mirjam Luijten, +14

Mutation Research/Genetic Toxicology and Environmental Mutagenesis

Translational MedicineInternational WorkshopToxicology TestingIntegrated Testing StrategyToxicology +4

A comparison of transgenic rodent mutation and in vivo comet assay responses for 91 chemicals

David Kirkland, Dan D. Levy, Matthew J. LeBaron, +24

Mutation Research/Genetic Toxicology and Environmental Mutagenesis

Identifying germ cell mutagens using OECD test guideline 488 (transgenic rodent somatic and germ cell gene mutation assays) and integration with somatic cell testing

Francesco Marchetti, Marilyn J. Aardema, Carol Beevers, +6

Mutation Research/Genetic Toxicology and Environmental Mutagenesis

FertilityGeneticsMolecular GeneticsGermline GeneticsSemen Analysis +22

New studies on the in vitro genotoxicity of sodium molybdate and their impact on the overall assessment of the genotoxicity of molybdenum substances

Arne Burzlaff, Carol Beevers, Helen Pearce, +2

Regulatory Toxicology and Pharmacology

Micronucleus test in rodent tissues other than liver or erythrocytes: Report of the IWGT working group

Yoshifumi Uno, Takeshi Morita, Mirjam Luijten, +5

Mutation Research/Genetic Toxicology and Environmental Mutagenesis

Laboratory HematologyHepatologyMedicineLiver PhysiologyBioanalysis +10

Simulation of mouse and rat spermatogenesis to inform genotoxicity testing using OECD test guideline 488

Francesco Marchetti, Marilyn J. Aardema, Carol Beevers, +6

Mutation Research/Genetic Toxicology and Environmental Mutagenesis

SpermatogenesisFertilityGeneticsReproductive HealthCell Population +21