Pedro Torres‐Ayuso

A small-molecule TNIK inhibitor targets fibrosis in preclinical and clinical models

Feng Ren, Alex Aliper, Jian Chen et al. · Nature Biotechnology · 2024 · 270 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

TNIK Is a Therapeutic Target in Lung Squamous Cell Carcinoma and Regulates FAK Activation through Merlin

Pedro Torres‐Ayuso, Elvira An, Katherine M. Nyswaner et al. · Cancer Discovery · 2021 · 57 citations · Full text

Medicine, Molecular Biology, Oncology +17

Diacylglycerol kinase ζ controls diacylglycerol metabolism at the immunological synapse

Severine Gharbi, Esther Rincón, Antonia Ávila‐Flores et al. · Molecular Biology of the Cell · 2011 · 50 citations

Life Sciences, Immunology, Molecular Biology +17

Diacylglycerol kinase α promotes 3D cancer cell growth and limits drug sensitivity through functional interaction with Src

Pedro Torres‐Ayuso, Manuel Daza-Martín, Jorge Martı́n-Pérez et al. · Oncotarget · 2014 · 47 citations · Full text

Medicine, Cancer Biology, Oncology +16

Survival of Head and Neck Cancer Cells Relies upon LZK Kinase-Mediated Stabilization of Mutant p53

Zoe C. Edwards, Eleanor W. Trotter, Pedro Torres‐Ayuso et al. · Cancer Research · 2017 · 40 citations

Life Sciences, Genetics, Oncology +13