Concepedia

Author

K. Coote

Novartis (United Kingdom)ORCID

Also Known As

Coote, K, K J Coote, K. Coote, Kevin Coote, Kevin J. Coote

33

Publications

448

Citations

9

H-Index

21

Concepts

All Affiliations

Novartis (United Kingdom)Novartis (Switzerland)Cystic Fibrosis FoundationNovartis FoundationMount Sinai Medical Center
KC

About

K. Coote is an author at Novartis (United Kingdom) specializing in medicine, pharmacology, and drug discovery.

Top Concepts

#ConceptH-IndexPublicationsCitations

1

Medicine

3

3

60

2

Natural Sciences

2

2

44

3

Biochemistry

2

2

44

4

Chemical Biology

1

1

28

5

Immunology

1

1

16

K. Coote

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9

Publications

418

Citations

9

H-Index

YearCitations

Chemical modifications of adenine base editor mRNA and guide RNA expand its application scope

Tingting Jiang, Jordana M. Henderson, K. Coote,

Nature Communications

2020

102

Camostat Attenuates Airway Epithelial Sodium Channel Function in Vivo through the Inhibition of a Channel-Activating Protease

K. Coote, Hazel C. Atherton-Watson, Rosemary Sugar,

Journal of Pharmacology and Experimental Therapeutics

2009

93

Characterization of cigarette smoke-induced inflammatory and mucus hypersecretory changes in rat lung and the role of CXCR2 ligands in mediating this effect

Christopher S. Stevenson, K. Coote, Ruth Webster,

American Journal of Physiology-Lung Cellular and Molecular Physiology

2004

91

A multimodal iPSC platform for cystic fibrosis drug testing

Andrew Berical, Rhianna E. Lee, Junjie Lu,

Nature Communications

2022

38

Discovery of a novel chemotype of potent human ENaC blockers using a bioisostere approach. Part 1: Quaternary amines

Thomas A. Hunt, Hazel C. Atherton-Watson, Jake Axford,

Bioorganic & Medicinal Chemistry Letters

2011

28

<scp>NVP</scp>‐<scp>QBE</scp>170: an inhaled blocker of the epithelial sodium channel with a reduced potential to induce hyperkalaemia

K. Coote, Derek Paisley, Sarah Czarnecki,

British Journal of Pharmacology

2015

21

MUCOCILIARY CLEARANCE IS ENHANCED IN RAT MODELS OF CIGARETTE SMOKE AND LIPOPOLYSACCHARIDE-INDUCED LUNG DISEASE

K. Coote, Andy Nicholls, Hazel C. Atherton,

Experimental Lung Research

2004

16

Discovery of a novel chemotype of potent human ENaC blockers using a bioisostere approach. Part 2: α-Branched quaternary amines

Thomas A. Hunt, Hazel C. Atherton-Watson, Stephen P. Collingwood,

Bioorganic & Medicinal Chemistry Letters

2012

16

The guinea‐pig tracheal potential difference as an <i>in vivo</i> model for the study of epithelial sodium channel function in the airways

K. Coote, Hazel C. Atherton, Allan H. Young,

British Journal of Pharmacology

2008

13

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