Biliary repair and carcinogenesis are mediated by IL-33–dependent cholangiocyte proliferation

Jun Li, Nataliya Razumilava, Gregory J. Gores, +8

Journal of Clinical Investigation

ImmunologyPathologyCell ProliferationCholangiopathiesCholangiocyte Biology +18

Growth Inhibition and Apoptosis in Liver Myofibroblasts Promoted by Hepatocyte Growth Factor Leads to Resolution from Liver Cirrhosis

Wook‐Hwan Kim, Kunio Matsumoto, Kazuhiko Bessho, +1

American Journal Of Pathology

HepatologyHepatocellular CarcinomaLiver PhysiologyLiver Myofibroblasts PromotedGrowth Inhibition +11

Wnt/Lrp/β-catenin signaling suppresses adipogenesis by inhibiting mutual activation of PPARγ and C/EBPα

Masanobu Kawai, Sotaro Mushiake, Kazuhiko Bessho, +5

Biochemical and Biophysical Research Communications

Systems BiologySignal TransductionSignaling PathwayPhysiologyMetabolic Signaling +8

Pharmacokinetics, Safety, and Efficacy of Glecaprevir/Pibrentasvir in Adolescents With Chronic Hepatitis C Virus: Part 1 of the DORA Study

Maureen M. Jonas, Robert H. Squires, Susan Rhee, +14

Hepatology

Part 1HepatologyHepatitis CAdolescent PatientsViral Hepatitis +11

Gene Expression Signature for Biliary Atresia and a Role for Interleukin-8 in Pathogenesis of Experimental Disease

Kazuhiko Bessho, Reena Mourya, Pranavkumar Shivakumar, +5

Hepatology

Clinical phenotype and endocrinological investigations in a patient with a mutation in the MCT8 thyroid hormone transporter

Noriyuki Namba, Yuri Etani, Taichi Kitaoka, +9

European Journal of Pediatrics

GeneticsThyroid DiseaseParathyroid HormoneGynecologyThyroid Disorders +7

Th2 signals induce epithelial injury in mice and are compatible with the biliary atresia phenotype

Jun Li, Kazuhiko Bessho, Pranavkumar Shivakumar, +6

Journal of Clinical Investigation

Replication of a GWAS signal in a Caucasian population implicates ADD3 in susceptibility to biliary atresia

Ellen Tsai, Christopher M. Grochowski, Kathleen M. Loomes, +7

Human Genetics

Genome-wide Association StudyAllelic VariantGenetic DisorderGeneticsGenetic Epidemiology +8

Recombinant Hepatocyte Growth Factor Accelerates Cutaneous Wound Healing in a Diabetic Mouse Model

Saho Yoshida, Kunio Matsumoto, D. Tomioka, +4

Growth Factors

Tissue EngineeringImmunologyDermatologySkin RegenerationRegenerative Medicine +16

Hepatocyte Growth Factor Suppresses Vascular Medial Hyperplasia and Matrix Accumulation in Advanced Pulmonary Hypertension of Rats

Masamichi Ono, Yoshiki Sawa, Shinya Mizuno, +5

Circulation