TIRAP, an Adaptor Protein for TLR2/4, Transduces a Signal from RAGE Phosphorylated upon Ligand Binding

Masakiyo Sakaguchi, Hitoshi Murata, Ken-ichi Yamamoto, +6

PLoS ONE

ImmunologyFunctional InteractionMolecular BiologySignal RecognitionLigand Binding +22

NRF2 Regulates PINK1 Expression under Oxidative Stress Conditions

Hitoshi Murata, Hitoshi Takamatsu, Sulai Liu, +3

PLoS ONE

InflammationPink1 GeneTranscriptional RegulationReductive StressMitochondrial Function +12

A New Cytosolic Pathway from a Parkinson Disease-associated Kinase, BRPK/PINK1

Hitoshi Murata, Masakiyo Sakaguchi, Jin Yu, +5

Journal of Biological Chemistry

MitophagyApoptosisMolecular BiologyCell DeathMitochondrial Biology +18

Truncation of Annexin A1 Is a Regulatory Lever for Linking Epidermal Growth Factor Signaling with Cytosolic Phospholipase A2 in Normal and Malignant Squamous Epithelial Cells

Masakiyo Sakaguchi, Hitoshi Murata, Hiroyuki Sonegawa, +5

Journal of Biological Chemistry

Molecular Cloning of an<i>aepA</i>Gene that Activates Production of Extracellular Pectolytic, Cellulolytic, and Proteolytic Enzymes in<i>Erwinia carotovora</i>subsp.<i>carotovora</i>

Hitoshi Murata

Molecular Plant-Microbe Interactions

BiologyBiosynthesisEngineeringVirulence FactorGenetics +10

S100A11, an Dual Mediator for Growth Regulation of Human Keratinocytes

Masakiyo Sakaguchi, Hiroyuki Sonegawa, Hitoshi Murata, +5

Molecular Biology of the Cell

Cell ProliferationDermatologyCancer BiologyCellular PhysiologyTumor Biology +18

c-Jun N-terminal kinase (JNK)-mediated phosphorylation of SARM1 regulates NAD+ cleavage activity to inhibit mitochondrial respiration

Hitoshi Murata, Cho Cho Khine, Akane Nishikawa, +3

Journal of Biological Chemistry

SARM1 and TRAF6 bind to and stabilize PINK1 on depolarized mitochondria

Hitoshi Murata, Masakiyo Sakaguchi, Ken Kataoka, +1

Molecular Biology of the Cell

MCAM, as a novel receptor for S100A8/A9, mediates progression of malignant melanoma through prominent activation of NF-κB and ROS formation upon ligand binding

I Made Winarsa Ruma, Endy Widya Putranto, Eisaku Kondo, +14

Clinical & Experimental Metastasis

Tumor BiologyNovel ReceptorMedicineMelanomaImmunology +8

Dramatic Increase in Expression of a Transgene by Insertion of Promoters Downstream of the Cargo Gene

Masakiyo Sakaguchi, Masami Watanabe, Rie Kinoshita, +12

Molecular Biotechnology