Toni Widmer

Discovery, Preclinical Characterization, and Early Clinical Activity of JDQ443, a Structurally Novel, Potent, and Selective Covalent Oral Inhibitor of KRASG12C

Andreas Weiss, Edwige Lorthiois, Louise Barys et al. · Cancer Discovery · 2022 · 130 citations · Full text

Transformation of acidic poorly water soluble drugs into ionic liquids

Anja Balk, Johannes Wiest, Toni Widmer et al. · European Journal of Pharmaceutics and Biopharmaceutics · 2015 · 86 citations

Ion Exchange, Ionic Liquids, Medicine +8

Ionic Liquid Versus Prodrug Strategy to Address Formulation Challenges

Anja Balk, Toni Widmer, Johannes Wiest et al. · Pharmaceutical Research · 2014 · 42 citations

Pharmaceutical Formulation, Medicine, Ionic Conductor +7

Mapping the pharmaceutical design space by amorphous ionic liquid strategies

Johannes Wiest, Marco Saedtler, Anja Balk et al. · Journal of Controlled Release · 2017 · 35 citations

Materials Science, Solid-state Ionic, Medicinal Chemistry +13

Discovery of the First Potent, Selective, and Orally Bioavailable Signal Peptide Peptidase-Like 2a (SPPL2a) Inhibitor Displaying Pronounced Immunomodulatory Effects In Vivo

Juraj Velcicky, Ursula Bodendorf, Pascal Rigollier et al. · Journal of Medicinal Chemistry · 2018 · 27 citations · Full text

Immunology, Sppl2a Knockout, Peptide Science +19