Essential role of protein kinase Bγ (PKBγ/Akt3) in postnatal brain development but not in glucose homeostasis

Oliver Tschopp, Zhong-Zhou Yang, Daniela Brodbeck, +6

Development

Brain DevelopmentCell DeathGlucose HomeostasisCellular PhysiologyInsulin Signaling +21

Protein Kinase Bα/Akt1 Regulates Placental Development and Fetal Growth

Zhongzhou Yang, Oliver Tschopp, Maja Hemmings-Mieszczak, +4

Journal of Biological Chemistry

Cell DeathPkb Alpha/akt1Cancer BiologyFetal GrowthTumor Biology +16

Life with a Single Isoform of Akt: Mice Lacking Akt2 and Akt3 Are Viable but Display Impaired Glucose Homeostasis and Growth Deficiencies

Bettina Dümmler, Oliver Tschopp, Debby Hynx, +3

Molecular and Cellular Biology

Single IsoformInsulin SignalingIsoform RedundancySignaling PathwayReceptor Tyrosine Kinase +17

Free fatty acids repress small heterodimer partner (SHP) activation and adiponectin counteracts bile acid-induced liver injury in superobese patients with nonalcoholic steatohepatitis

Lars P. Bechmann, Peri Kocabayoglu, Jan‐Peter Sowa, +14

Hepatology

Toll-like receptor 2-deficient mice are protected from insulin resistance and beta cell dysfunction induced by a high-fat diet

Jan A. Ehses, Daniel T. Meier, Stephan Wueest, +19

Diabetologia

ObesityMetabolic SyndromeInflammationInsulin ResistanceAutoimmune Disease +9

Dosage-Dependent Effects of Akt1/Protein Kinase Bα (PKBα) and Akt3/PKBγ on Thymus, Skin, and Cardiovascular and Nervous System Development in Mice

Zhongzhou Yang, Oliver Tschopp, Nicolas Di-Poı̈, +5

Molecular and Cellular Biology

Akt1/protein Kinase BαGeneticsApoptosisImmunologyCell Death +17

Liver Failure After Extended Hepatectomy in Mice Is Mediated by a p21-Dependent Barrier to Liver Regeneration

Kuno Lehmann, Christoph Tschuor, Andreas Rickenbacher, +9

Gastroenterology

Liver FailureHepatologyLiver PhysiologyLiver RegenerationPathology +12

Protective effects of farnesoid X receptor (FXR) on hepatic lipid accumulation are mediated by hepatic FXR and independent of intestinal FGF15 signal

Johannes Schmitt, Bo Kong, Bruno Stieger, +7

Liver International

Osteoporosis Before Lung Transplantation: Association with Low Body Mass Index, but Not with Underlying Disease

Oliver Tschopp, Annette Boehler, Rudolf Speich, +4

American Journal of Transplantation

Treatment of non-alcoholic steatohepatitis patients with vitamin D: a double-blinded, randomized, placebo-controlled pilot study

Andreas Geier, Mareile L. Eichinger, Guido Stirnimann, +11

Scandinavian Journal of Gastroenterology