Alys Peisley

Structural Basis for dsRNA Recognition, Filament Formation, and Antiviral Signal Activation by MDA5

Bin Wu, Alys Peisley, Claire Richards et al. · Cell · 2012 · 552 citations

Filament Formation, Rna Biology, Molecular Biology +6

Structural basis for ubiquitin-mediated antiviral signal activation by RIG-I

Alys Peisley, Bin Wu, Hui Xu et al. · Nature · 2014 · 312 citations · Full text

Immunology, Antiviral Drug Development, Antiviral Response +5

Cooperative assembly and dynamic disassembly of MDA5 filaments for viral dsRNA recognition

Alys Peisley, Cecilie Lin, Bin Wu et al. · Proceedings of the National Academy of Sciences · 2011 · 306 citations · Full text

Viral Replication, Cooperative Assembly, Protein Assembly +19

MDA5 Detects the Double-Stranded RNA Replicative Form in Picornavirus-Infected Cells

Feng Qian, Stanleyson V. Hato, Martijn A. Langereis et al. · Cell Reports · 2012 · 242 citations · Full text

Viral Replication, Viral Polymerase Mechanism, Immunology +19

Molecular Imprinting as a Signal-Activation Mechanism of the Viral RNA Sensor RIG-I

Bin Wu, Alys Peisley, David G Tetrault et al. · Molecular Cell · 2014 · 241 citations · Full text

Viral Replication, Natural Sciences, Immunology +8