PRMT2 links histone H3R8 asymmetric dimethylation to oncogenic activation and tumorigenesis of glioblastoma

Feng Dong, Qian Li, Chao Yang, +13

Nature Communications

Ubiquitin ligase RNF20/40 facilitates spindle assembly and promotes breast carcinogenesis through stabilizing motor protein Eg5

Yang Duan, Dawei Huo, Jie Gao, +13

Nature Communications

Breast OncologyMolecular RegulationMolecular BiologyCell CycleCancer Biology +15

JMJD6 modulates DNA damage response through downregulating H4K16ac independently of its enzymatic activity

Dawei Huo, Hao Chen, Yiming Cheng, +4

Cell Death and Differentiation

Histone ModificationsMolecular BiologyEpigeneticsRedox BiologyDna Lesions +17

Abnormal neocortex arealization and Sotos-like syndrome–associated behavior in <i>Setd2</i> mutant mice

Lichao Xu, Yue Zheng, Xuejing Li, +10

Science Advances

Nuclear DEK preserves hematopoietic stem cells potential via NCoR1/HDAC3-Akt1/2-mTOR axis

Zhe Chen, Dawei Huo, Lei Li, +15

The Journal of Experimental Medicine

Mixed-phenotype Acute LeukemiaGeneticsEpigeneticsMyeloid NeoplasiaHematological Malignancy +16

Generation and validation of versatile inducible CRISPRi embryonic stem cell and mouse model

Rui Li, Xianyou Xia, Xing Wang, +7

PLoS Biology

Induced Pluripotent Stem CellOff-target EffectDevelopmental BiologyMedicineKi Mouse +12

Enhancer reprogramming promotes the activation of cancer-associated fibroblasts and breast cancer metastasis

Qian Li, Xuejiao Lv, Chunyong Han, +12

Theranostics

DOT1L promotes angiogenesis through cooperative regulation of VEGFR2 with ETS-1

Yang Duan, Xue Wu, Qiang Zhao, +8

Oncotarget

Histone Methyltransferase Dot1lAngiogenesisDevelopmental BiologyNatural SciencesGene Expression +12

CpG island reconfiguration for the establishment and synchronization of polycomb functions upon exit from naive pluripotency

Dawei Huo, Zhaowei Yu, Rui Li, +14

Molecular Cell

EngineeringPolycomb FunctionsComputer EngineeringFormal MethodsCpg Island Reconfiguration +3

mTORC2 regulates hierarchical micro/nano topography‐induced osteogenic differentiation via promoting cell adhesion and cytoskeletal polymerization

Qian Gao, Yuying Hou, Zhe Li, +8

Journal of Cellular and Molecular Medicine