Prafulla Aryal

K2P channel gating mechanisms revealed by structures of TREK-2 and a complex with Prozac

Yin Yao Dong, A.C.W. Pike, Alexandra Mackenzie et al. · Science · 2015 · 305 citations · Full text

Pharmacological Blockade of the Cold Receptor TRPM8 Attenuates Autonomic and Behavioral Cold Defenses and Decreases Deep Body Temperature

Maria Camila Almeida, Tamara Hew‐Butler, Renato Nery Soriano et al. · Journal of Neuroscience · 2012 · 257 citations · Full text

Cutaneous Trpm8 Channels, Immunology, Trpm8 Channels +19

Neurotransmitter Acetylcholine Negatively Regulates Neuromuscular Synapse Formation by a Cdk5-Dependent Mechanism

Weichun Lin, Bertha Dominguez, Jiefei Yang et al. · Neuron · 2005 · 221 citations · Full text

Neurotransmitter, Cdk5-dependent Mechanism, Neurotransmission +17

A discrete alcohol pocket involved in GIRK channel activation

Prafulla Aryal, Hay Dvir, Senyon Choe et al. · Nature Neuroscience · 2009 · 164 citations · Full text

Molecular Physiology, Discrete Alcohol Pocket, Medicine +4

A hydrophobic barrier deep within the inner pore of the TWIK-1 K2P potassium channel

Prafulla Aryal, Firdaus Abd-Wahab, Giovanna Bucci et al. · Nature Communications · 2014 · 133 citations · Full text