Concepedia

Tuyen Nguyen

TN

Statistics

Publications

15

Citations

1.1K

H-Index

13

Active since

2013

Affiliations

Alnylam Pharmaceuticals (United States)(Current)

Vanderbilt University

Tuyen Nguyen is an author at Alnylam Pharmaceuticals (United States) specializing in medicine, gene expression, and liver physiology.

ORCID

Top concepts

Publications per year

2013–2023

15

Publications

15

Expanding RNAi therapeutics to extrahepatic tissues with lipophilic conjugates

Kirk Brown, Jayaprakash K. Nair, Maja M. Janas et al. · Nature Biotechnology · 2022 · 225 citations · Full text

, , +5

siRNA Conjugates Carrying Sequentially Assembled Trivalent <i>N-</i>Acetylgalactosamine Linked Through Nucleosides Elicit Robust Gene Silencing <i>In Vivo</i> in Hepatocytes

Shigeo Matsuda, Kristofer Keiser, Jayaprakash K. Nair et al. · ACS Chemical Biology · 2015 · 206 citations

Hepatocyte‐Specific Delivery of siRNAs Conjugated to Novel Non‐nucleosidic Trivalent <i>N</i>‐Acetylgalactosamine Elicits Robust Gene Silencing in Vivo

Kallanthottathil G. Rajeev, Jayaprakash K. Nair, Muthusamy Jayaraman et al. · ChemBioChem · 2015 · 180 citations

, , +20

Evaluation of GalNAc-siRNA Conjugate Activity in Pre-clinical Animal Models with Reduced Asialoglycoprotein Receptor Expression

Jennifer L. S. Willoughby, Amy Chan, Alfica Sehgal et al. · Molecular Therapy · 2017 · 106 citations · Full text

From bench to bedside: Improving the clinical safety of GalNAc–siRNA conjugates using seed-pairing destabilization

Mark K. Schlegel, Maja M. Janas, Yongfeng Jiang et al. · Nucleic Acids Research · 2022 · 84 citations · Full text

1–5 of 15