Akifumi Kushiyama

AMP-activated Protein Kinase Activation Increases Phosphorylation of Glycogen Synthase Kinase 3β and Thereby Reduces cAMP-responsive Element Transcriptional Activity and Phosphoenolpyruvate Carboxykinase C Gene Expression in the Liver

Nanao Horike, Hideyuki Sakoda, Akifumi Kushiyama et al. · Journal of Biological Chemistry · 2008 · 188 citations · Full text

Transcriptional Regulation, Signal Transduction, Signaling Pathway +14

Oxidative stress induces insulin resistance by activating the nuclear factor-?B pathway and disrupting normal subcellular distribution of phosphatidylinositol 3-kinase

Takehide Ogihara, Tomoichiro Asano, Hideki Katagiri et al. · Diabetologia · 2004 · 146 citations · Full text

Metabolic Remodeling, Insulin Signaling, Nuclear Factor- +17

Xanthine Oxidoreductase Is Involved in Macrophage Foam Cell Formation and Atherosclerosis Development

Akifumi Kushiyama, Hirofumi Okubo, Hideyuki Sakoda et al. · Arteriosclerosis Thrombosis and Vascular Biology · 2011 · 122 citations · Full text

Treatment with the SGLT2 inhibitor luseogliflozin improves nonalcoholic steatohepatitis in a rodent model with diabetes mellitus

Shirong Qiang, Yusuke Nakatsu, Yasuyuki Seno et al. · Diabetology & Metabolic Syndrome · 2015 · 112 citations · Full text

<i>Lactobacillus casei</i>strain Shirota protects against nonalcoholic steatohepatitis development in a rodent model

Hirofumi Okubo, Hideyuki Sakoda, Akifumi Kushiyama et al. · American Journal of Physiology-Gastrointestinal and Liver Physiology · 2013 · 101 citations

Nutrition, Dysbiosis, Rodent Model +17