Alzheimer's Disease-Like Tau Neuropathology Leads to Memory Deficits and Loss of Functional Synapses in a Novel Mutated Tau Transgenic Mouse without Any Motor Deficits

Katharina Schindowski, Alexis Bretteville, Karelle Leroy, +4

American Journal Of Pathology

Specificity of Anti-Tau Antibodies when Analyzing Mice Models of Alzheimer's Disease: Problems and Solutions

Franck R. Petry, Jérôme Pelletier, Alexis Bretteville, +5

PLoS ONE

Transgenic Mouse ModelsImmunologyPathologyNeurochemical BiomarkersAnti-tau Antibodies +21

Acceleration and persistence of neurofibrillary pathology in a mouse model of tauopathy following anesthesia

Emmanuel Planel, Alexis Bretteville, Li Liu, +6

The FASEB Journal

Tau PathologyNeurofibrillary PathologyNeurochemical BiomarkersSocial SciencesAlzheimer's Disease +16

Early Axonopathy Preceding Neurofibrillary Tangles in Mutant Tau Transgenic Mice

Karelle Leroy, Alexis Bretteville, Katharina Schindowski, +6

American Journal Of Pathology

Neurodegenerative DiseasesMolecular NeuroscienceDegenerative DiseaseDegenerative PathologyNeurology +6

Functional screening of Alzheimer risk loci identifies PTK2B as an in vivo modulator and early marker of Tau pathology

Pierre Dourlen, Francisco-José Fernández-Gómez, Clément Dupont, +18

Molecular Psychiatry

A transgenic rat that develops Alzheimer's disease-like amyloid pathology, deficits in synaptic plasticity and cognitive impairment

Li Liu, Ian J. Orozco, Emmanuel Planel, +9

Neurobiology of Disease

Synaptic PlasticityNeurodegenerative DiseasesDevelopmental BiologyAlzheimer's DiseaseDementia +11

p25/Cdk5-mediated retinoblastoma phosphorylation is an early event in neuronal cell death

Malika Hamdane, Alexis Bretteville, Anne‐Véronique Sambo, +5

Journal of Cell Science

Neuronal Cell DeathApoptosisImmunologyRetinoblastoma ProteinCell Death +20

Tau phosphorylation regulates the interaction between BIN1’s SH3 domain and Tau’s proline-rich domain

Yoann Sottejeau, Alexis Bretteville, François‐Xavier Cantrelle, +15

Acta Neuropathologica Communications

Pin1 allows for differential Tau dephosphorylation in neuronal cells

Malika Hamdane, Pierre Dourlen, Alexis Bretteville, +12

Molecular and Cellular Neuroscience

Cellular NeurobiologyMolecular NeuroscienceSignal TransductionDegenerative PathologyMolecular Neurobiology +3

Anesthesia-Induced Hyperphosphorylation Detaches 3-Repeat Tau from Microtubules without Affecting Their Stability<i>In Vivo</i>

Emmanuel Planel, Pavan Krishnamurthy, Tomohiro Miyasaka, +11

Journal of Neuroscience