Mohammad Azam

Lin28 promotes transformation and is associated with advanced human malignancies

Srinivas R. Viswanathan, John T. Powers, William S. Einhorn et al. · Nature Genetics · 2009 · 814 citations · Full text

Tumor Biology, Oncology, Oncogenic Agent +9

Mechanisms of Autoinhibition and STI-571/Imatinib Resistance Revealed by Mutagenesis of BCR-ABL

Mohammad Azam, Robert Latek, George Q. Daley · Cell · 2003 · 623 citations · Full text

Chromatin Remodeling, Sti-571/imatinib Resistance, Molecular Biology +3

Targeting Bcr–Abl by combining allosteric with ATP-binding-site inhibitors

Jianming Zhang, Francisco Adrián, Wolfgang Jahnke et al. · Nature · 2010 · 590 citations

Molecular Pharmacology, Drug Target, Medicine +5

Activation of tyrosine kinases by mutation of the gatekeeper threonine

Mohammad Azam, Markus A. Seeliger, Nathanael S. Gray et al. · Nature Structural & Molecular Biology · 2008 · 414 citations · Full text

Signal Transduction, Molecular Regulation, Receptor Tyrosine Kinase +6

Activity of dual SRC-ABL inhibitors highlights the role of BCR/ABL kinase dynamics in drug resistance

Mohammad Azam, Valentina Nardi, William C. Shakespeare et al. · Proceedings of the National Academy of Sciences · 2006 · 108 citations · Full text

Conformational Dynamics, Drug Target, Imatinib Binding +20