Cannabinoids ablate release of TNFα in rat microglial cells stimulated with lypopolysaccharide

Fabrizio Facchinetti, Elda Del Giudice, Sara Furegato, +2

Glia

Transient Receptor Potential Ankyrin 1 Channel Localized to Non-Neuronal Airway Cells Promotes Non-Neurogenic Inflammation

Romina Nassini, Pamela Pedretti, Nadia Moretto, +13

PLoS ONE

α,β-Unsaturated Aldehydes in Cigarette Smoke Release Inflammatory Mediators from Human Macrophages

Fabrizio Facchinetti, Francesco Amadei, Pierangelo Geppetti, +7

American Journal of Respiratory Cell and Molecular Biology

InflammationAnti-inflammatoryMimic CseInflammatory Lung DiseaseCse-evoked Il-8 Release +11

α,β-Unsaturated aldehydes contained in cigarette smoke elicit IL-8 release in pulmonary cells through mitogen-activated protein kinases

Nadia Moretto, Fabrizio Facchinetti, Thomas Southworth, +3

American Journal of Physiology-Lung Cellular and Molecular Physiology

Synthesis and Biological Activity of Flurbiprofen Analogues as Selective Inhibitors of β-Amyloid₁_-₄₂Secretion

Ilaria Peretto, Stefano Radaelli, Carlo Parini, +21

Journal of Medicinal Chemistry

Pharmaceutical ScienceSelective InhibitorsPharmacotherapyPharmaceutical ChemistryMolecular Pharmacology +18

Differential Susceptibility to Neurotoxicity Mediated by Neurotrophins and Neuronal Nitric Oxide Synthase

Amer F. Samdani, Cheryl Newcamp, Annelies Resink, +4

Journal of Neuroscience

Nitric OxideNnos ExpressionNeurotoxicity MediatedOxidative StressReactive Nitrogen Specie +14

Cigarette smoke and its component acrolein augment IL-8/CXCL8 mRNA stability via p38 MAPK/MK2 signaling in human pulmonary cells

Nadia Moretto, Serena Bertolini, Claudia Iadicicco, +6

American Journal of Physiology-Lung Cellular and Molecular Physiology

AsthmaCse ExposureLung InflammationImmunologyCell Death +15

Lack of involvement of neuronal nitric oxide synthase in the pathogenesis of a transgenic mouse model of familial amyotrophic lateral sclerosis

Fabrizio Facchinetti, Masayuki Sasaki, Frank B. Cutting, +8

Neuroscience

CHF5074, a novel γ‐secretase modulator, attenuates brain β‐amyloid pathology and learning deficit in a mouse model of Alzheimer's disease

Birgit Hutter‐Paier, Gino Villetti, Fabrizio Facchinetti, +5

British Journal of Pharmacology

Structural, neurochemical and behavioural consequences of neonatal blockade of NMDA receptor through chronic treatment with CGP 39551 or MK-801

Fabrizio Facchinetti, Elisabetta Ciani, R. DallʼOlio, +3

Developmental Brain Research

Neonatal BlockadeNeurophysiologyMedicineFunctional SelectivityBehavioral Pharmacology +10