AS04, an Aluminum Salt- and TLR4 Agonist-Based Adjuvant System, Induces a Transient Localized Innate Immune Response Leading to Enhanced Adaptive Immunity

Arnaud M. Didierlaurent, Sandra Morel, Laurence Lockman, +10

The Journal of Immunology

Adaptive Immune SystemInnate Immune SystemImmunologyImmunologic MechanismCd4 T Cell Responses +18

Toll-like receptor 4 stimulation with the detoxified ligand monophosphoryl lipid A improves Alzheimer’s disease-related pathology

Jean-Philippe Michaud, Maxime Hallé, Antoine Lampron, +12

Proceedings of the National Academy of Sciences

Nuclear Retention of MBP mRNAs in the Quaking Viable Mice

Daniel Larocque, Julie Pilotte, Taiping Chen, +7

Neuron

Knockout MouseEngineeringNuclear RetentionRna BiologySystems Biology +4

Protection of p27Kip1 mRNA by quaking RNA binding proteins promotes oligodendrocyte differentiation

Daniel Larocque, André Galarneau, Hsueh‐Ning Liu, +3

Nature Neuroscience

Developmental BiologyP27kip1 MrnaRna BiologyProteins PromotesGene Expression +3

Tyrosine Phosphorylation of Sam68 by Breast Tumor Kinase Regulates Intranuclear Localization and Cell Cycle Progression

Kiven Erique Lukong, Daniel Larocque, Angela L. Tyner, +1

Journal of Biological Chemistry

Cell CycleTumor BiologySignaling PathwayCell RegulationReceptor Tyrosine Kinase +14

Nuclear translocation controlled by alternatively spliced isoforms inactivates the QUAKING apoptotic inducer

Julie Pilotte, Daniel Larocque, Stéphane Richard

Genes & Development

Quaking Apoptotic InducerApoptosisMolecular BiologyCell DeathSpliced Qki Isoforms +17

One-year Expression From High-capacity Adenoviral Vectors in the Brains of Animals With Pre-existing Anti-adenoviral Immunity: Clinical Implications

Carlos Barcia, Maximiliano Jimenez-Dalmaroni, Kurt M. Kroeger, +13

Molecular Therapy

Combined Flt3L/TK Gene Therapy Induces Immunological Surveillance Which Mediates an Immune Response Against a Surrogate Brain Tumor Neoantigen

Gwendalyn D. King, AKM Ghulam Muhammad, Daniel Larocque, +7

Molecular Therapy

The QKI-6 and QKI-7 RNA Binding Proteins Block Proliferation and Promote Schwann Cell Myelination

Daniel Larocque, Gabriela Fragoso, Jinghan Huang, +4

PLoS ONE

The p53 Tumor Suppressor Is Stabilized by Inhibitor of Growth 1 (ING1) by Blocking Polyubiquitination

Subhash Thalappilly, Xiaolan Feng, Svitlana Pastyryeva, +5

PLoS ONE

ApoptosisCell DeathMolecular BiologyCancer BiologyTumor Biology +16