Monica Pallis

P-glycoprotein plays a drug-efflux–independent role in augmenting cell survival in acute myeloblastic leukemia and is associated with modulation of a sphingomyelin-ceramide apoptotic pathway

Monica Pallis, Nigel H. Russell · Blood · 2000 · 158 citations

The impact of dose escalation and resistance modulation in older patients with acute myeloid leukaemia and high risk myelodysplastic syndrome: the results of the LRF AML14 trial

Alan K. Burnett, Donald Milligan, Anthony P. Goldstone et al. · British Journal of Haematology · 2009 · 140 citations

Mixed-phenotype Acute Leukemia, Pharmacotherapy, Myeloid Neoplasia +16

DNA repair contributes to the drug-resistant phenotype of primary acute myeloid leukaemia cells with FLT3 internal tandem duplications and is reversed by the FLT3 inhibitor PKC412

Claire Seedhouse, Hannah Hunter, Bethan Lloyd‐Lewis et al. · Leukemia · 2006 · 81 citations

Hematological Malignancy, Genome Instability, Drug-resistant Phenotype +10

Bcl-xL is heterogeneously expressed by acute myeloblastic leukaemia cells and is associated with autonomous growth in vitro and with P-glycoprotein expression

Monica Pallis, Y‐M Zhu, N. H. Russell · Leukemia · 1997 · 53 citations

Hematological Malignancy, Mixed-phenotype Acute Leukemia, Malignant Blood Disorder +9

P-glycoprotein is implicated in the inhibition of ceramide-induced apoptosis in TF-1 acute myeloid leukemia cells by modulation of the glucosylceramide synthase pathway

Julie Turzanski, Martin Grundy, Shilli Shang et al. · Experimental Hematology · 2005 · 50 citations · Full text

Hematological Malignancy, Glucosylceramide Synthase Pathway, Medicine +9