Structure of the FANCI-FANCD2 Complex: Insights into the Fanconi Anemia DNA Repair Pathway

Woo S. Joo, Guozhou Xu, Nicole S. Persky, +5

Science

ChromatinGenome InstabilityFanconi AnemiaCrystal StructureMolecular Research +11

SAMHD1 suppresses innate immune responses to viral infections and inflammatory stimuli by inhibiting the NF-κB and interferon pathways

Shuliang Chen, Serena Bonifati, Zhihua Qin, +13

Proceedings of the National Academy of Sciences

Expanding the clinical, allelic, and locus heterogeneity of retinal dystrophies

Nisha Patel, Mohammed A. Aldahmesh, Hisham Alkuraya, +27

Genetics in Medicine

Ocular DiseaseRetinaOphthalmologyGeneticsLocus Heterogeneity +2

Role of the Pif1-PCNA Complex in Pol δ-Dependent Strand Displacement DNA Synthesis and Break-Induced Replication

Olga Buzovetsky, Youngho Kwon, Nhung Pham, +4

Cell Reports

Selective inactivation of hypomethylating agents by SAMHD1 provides a rationale for therapeutic stratification in AML

Thomas Oellerich, Constanze Schneider, Dominique Thomas, +21

Nature Communications

Promotion of RAD51-Mediated Homologous DNA Pairing by the RAD51AP1-UAF1 Complex

Fengshan Liang, Simonne Longerich, Adam S. Miller, +7

Cell Reports

Insights into DNA substrate selection by APOBEC3G from structural, biochemical, and functional studies

Samantha J. Ziegler, Chang Liu, Mark J. Landau, +8

PLoS ONE

The structural basis for cancer drug interactions with the catalytic and allosteric sites of SAMHD1

Kirsten M. Knecht, Olga Buzovetsky, Constanze Schneider, +12

Proceedings of the National Academy of Sciences

Conformational switches control early maturation of the eukaryotic small ribosomal subunit

Mirjam Hunziker, Jonas Barandun, Olga Buzovetsky, +3

eLife

SAMHD1 Impairs HIV-1 Gene Expression and Negatively Modulates Reactivation of Viral Latency in CD4 ⁺ T Cells

Jenna M. Antonucci, Sun‐Hee Kim, Corine St. Gelais, +8

Journal of Virology