Rebecca Broome

IL6/STAT3 Signaling Hijacks Estrogen Receptor α Enhancers to Drive Breast Cancer Metastasis

Rasmus Siersbæk, Valentina Scabia, Sankari Nagarajan et al. · Cancer Cell · 2020 · 258 citations · Full text

Medicine, Cancer Biology, Oncology +14

Wnt/β-catenin and FGF signalling direct the specification and maintenance of a neuromesodermal axial progenitor in ensembles of mouse embryonic stem cells

David A. Turner, Penelope Hayward, Peter Baillie‐Johnson et al. · Development · 2014 · 177 citations · Full text

Life Sciences, Cell Biology, Developmental Biology +17

Optimization of TEAD P-Site Binding Fragment Hit into In Vivo Active Lead <b>MSC-4106</b>

Timo Heinrich, Carl R. Peterson, Richard Schneider et al. · Journal of Medicinal Chemistry · 2022 · 77 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

TET2 is a component of the estrogen receptor complex and controls 5mC to 5hmC conversion at estrogen receptor cis-regulatory regions

Rebecca Broome, Igor Chernukhin, Stacey Jamieson et al. · Cell Reports · 2021 · 59 citations · Full text

Medicine, Cancer Biology, Molecular Biology +16

The inhibition of human lung fibroblast proliferation and differentiation by Gs-coupled receptors is not predicted by the magnitude of cAMP response

Maxine J. Roberts, Rebecca Broome, Toby Kent et al. · Respiratory Research · 2018 · 34 citations · Full text

Life Sciences, Molecular Biology, Pharmacology +17