Concepedia

Hans Zempel

HZ

16

Publications

1.8K

Citations

15

H-Index

2010

Active since

Affiliations

University Hospital Cologne(Current)

German Center for Neurodegenerative Diseases

University of Cologne

Center of Advanced European Studies and Research

Max Planck Unit for Structural Molecular Biology

Hans Zempel is an author at University Hospital Cologne specializing in medicine, social sciences, and neuroscience.

ORCID

Top concepts

Publications per year

2010–2025

16

Publications

16

Aβ Oligomers Cause Localized Ca <sup>2+</sup> Elevation, Missorting of Endogenous Tau into Dendrites, Tau Phosphorylation, and Destruction of Microtubules and Spines

Hans Zempel, Edda Thies, Eckhard Mandelkow� et al. · Journal of Neuroscience · 2010 · 657 citations · Full text

Amyloid‐β oligomers induce synaptic damage via Tau‐dependent microtubule severing by TTLL6 and spastin

Hans Zempel, Julia Luedtke, Yatender Kumar et al. · The EMBO Journal · 2013 · 274 citations · Full text

Novel diffusion barrier for axonal retention of Tau in neurons and its failure in neurodegeneration

Xiaoyu Li, Yatender Kumar, Hans Zempel et al. · The EMBO Journal · 2011 · 223 citations · Full text

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Axodendritic sorting and pathological missorting of Tau are isoform-specific and determined by axon initial segment architecture

Hans Zempel, Frank J.A. Dennissen, Yatender Kumar et al. · Journal of Biological Chemistry · 2017 · 146 citations · Full text

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Endo-lysosomal Aβ concentration and pH trigger formation of Aβ oligomers that potently induce Tau missorting

Marie P. Schützmann, Filip Hasecke, Sarah Bachmann et al. · Nature Communications · 2021 · 122 citations · Full text

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