Baricitinib treatment resolves lower-airway macrophage inflammation and neutrophil recruitment in SARS-CoV-2-infected rhesus macaques

Timothy N. Hoang, María Pino, Arun K. Boddapati, +42

Cell

InflammationCytokineBaricitinib TreatmentLung InflammationInnate Immune System +6

Whole-body immunoPET reveals active SIV dynamics in viremic and antiretroviral therapy–treated macaques

Philip J. Santangelo, Kenneth A. Rogers, Chiara Zurla, +13

Nature Methods

Viral PersistenceHuman RetrovirusImmunologyAntiviral ResponseAntiviral Therapy +5

A vaccine targeting resistant tumours by dual T cell plus NK cell attack

S Badrinath, Maxence O. Dellacherie, Aileen W. Li, +14

Nature

VaccinationResistant TumoursImmunologyTumor ImmunityDual T Cell +7

Aerosolized oxytocin increases cerebrospinal fluid oxytocin in rhesus macaques

Meera E. Modi, Fawn Connor‐Stroud, Rainer Landgraf, +2

Psychoneuroendocrinology

Animal PhysiologyNeurophysiologyPhysiologyNeuroendocrine MechanismNeuroscience +3

A modified vaccinia Ankara vector-based vaccine protects macaques from SARS-CoV-2 infection, immune pathology, and dysfunction in the lungs

Nanda Kishore Routhu, Narayanaiah Cheedarla, Sailaja Gangadhara, +29

Immunity

VaccinationVaccine DevelopmentImmune PathologySars-cov-2 InfectionImmunology +4

A yeast-expressed RBD-based SARS-CoV-2 vaccine formulated with 3M-052-alum adjuvant promotes protective efficacy in non-human primates

María Pino, Talha Abid, Susan Pereira Ribeiro, +44

Science Immunology

VaccinationMucosal VaccinationRbd ImmunogenVaccine DevelopmentVaccine Target +9

Germline transmission in transgenic Huntington's disease monkeys

Sean P. Moran, Tim Chi, Melinda S. Prucha, +5

Theriogenology

Knockout MouseMedicineGeneticsGermline TransmissionGene Transfer

Modulation of type I interferon responses potently inhibits SARS-CoV-2 replication and inflammation in rhesus macaques

Elise G. Viox, Timothy N. Hoang, Amit A. Upadhyay, +39

Science Immunology

Dynamics and origin of rebound viremia in SHIV-infected infant macaques following interruption of long-term ART

Veronica Obregon-Perko, Katherine M. Bricker, Gloria Mensah, +19

JCI Insight

ImmunologyViral DynamicPathologyPlasma VirusImmunotherapy +15