Ginseng polysaccharides alter the gut microbiota and kynurenine/tryptophan ratio, potentiating the antitumour effect of antiprogrammed cell death 1/programmed cell death ligand 1 (anti-PD-1/PD-L1) immunotherapy

Jumin Huang, Di Liu, Yuwei Wang, +31

Gut

Luteolin and its derivative apigenin suppress the inducible PD-L1 expression to improve anti-tumor immunity in KRAS-mutant lung cancer

Zebo Jiang, Wenjun Wang, Cong Xu, +14

Cancer Letters

Derivative ApigeninMedicineOncogenic AgentImmunologyTumor Immunity +8

Evodiamine suppresses non-small cell lung cancer by elevating CD8+ T cells and downregulating the MUC1-C/PD-L1 axis

Zebo Jiang, Jumin Huang, Ya‐Jia Xie, +10

Journal of Experimental & Clinical Cancer Research

Metabolomics and integrated network pharmacology analysis reveal Tricin as the active anti-cancer component of Weijing decoction by suppression of PRKCA and sphingolipid signaling

Jiaxin Li, Runze Li, Ao Sun, +17

Pharmacological Research

Chemoprevention StrategyBiochemistryMedicineSphingolipid SignalingMetabolomic Profiling +7

Cordycepin Inhibits Drug-resistance Non-small Cell Lung Cancer Progression by Activating AMPK Signaling Pathway

Chunli Wei, Xiaojun Yao, Zebo Jiang, +8

Pharmacological Research

Tumor BiologyChemoprevention StrategyMedicinePharmacologyBronchial Neoplasm +8

Shikonin inhibits gefitinib-resistant non-small cell lung cancer by inhibiting TrxR and activating the EGFR proteasomal degradation pathway

Xia Li, Xing‐Xing Fan, Zebo Jiang, +5

Pharmacological Research

MedicinePathologyBronchial NeoplasmCancer BiologyCancer Treatment +5

β-Elemene enhances erlotinib sensitivity through induction of ferroptosis by upregulating lncRNA H19 in EGFR-mutant non-small cell lung cancer

Cong Xu, Zebo Jiang, Le Shao, +13

Pharmacological Research

Chemoprevention StrategyCancer BiologyTumor BiologyMetronomic TherapyCancer Cell Biology +14

SCD1 is associated with tumor promotion, late stage and poor survival in lung adenocarcinoma

Jun Huang, Xing‐Xing Fan, Jiaxi He, +8

Oncotarget

Lung AdenocarcinomaPathologyMetabolic RemodelingWarburg EffectCancer Biology +15

Andrographolide suppresses non-small-cell lung cancer progression through induction of autophagy and antitumor immune response

Xuan‐Run Wang, Zebo Jiang, Cong Xu, +12

Pharmacological Research

Cell AutophagyAntitumor Immune ResponseLung InflammationMedicineImmunology +10

Glycyrrhizin Suppresses Lung Adenocarcinoma Cell Growth Through Inhibition of Thromboxane Synthase

Run-Yue Huang, Yong‐Liang Chu, Zebo Jiang, +3

Cellular Physiology and Biochemistry

Chemoprevention StrategyTxas SirnaCancer BiologyTumor BiologyCancer Cell Biology +14