TGF-β activates Akt kinase through a microRNA-dependent amplifying circuit targeting PTEN

Mitsuo Kato, Sumanth Putta, Mei Wang, +8

Nature Cell Biology

Signal TransductionSignaling PathwayCell RegulationMicrorna DetectionSystems Biology +4

I-SceI-Based Assays to Examine Distinct Repair Outcomes of Mammalian Chromosomal Double Strand Breaks

Amanda Gunn, Jeremy M. Stark

Methods in molecular biology

The Influence of Non-Nociceptive Factors on Hot-Plate Latency in Rats

Amanda Gunn, Erin N. Bobeck, Ceri Weber, +1

Journal of Pain

Hot-plate LatencyHealth SciencesBehavioral NeuroscienceNeurophysiologyPain Medicine +10

BAF facilitates interphase nuclear membrane repair through recruitment of nuclear transmembrane proteins

Alexandra M. Young, Amanda Gunn, Emily Hatch

Molecular Biology of the Cell

Nuclear Transmembrane ProteinsMolecular BiologyNuclear MembraneAutophagySecretory Pathway +16

Correct End Use during End Joining of Multiple Chromosomal Double Strand Breaks Is Influenced by Repair Protein RAD50, DNA-dependent Protein Kinase DNA-PKcs, and Transcription Context

Amanda Gunn, Nicole Bennardo, Anita Cheng, +1

Journal of Biological Chemistry

Dna DamageEnd JoiningGeneticsGenomic MechanismMolecular Biology +14

Limiting the Persistence of a Chromosome Break Diminishes Its Mutagenic Potential

Nicole Bennardo, Amanda Gunn, Anita Cheng, +2

PLoS Genetics

Dna DamageGeneticsMutagenic PotentialMolecular BiologyChromosome Break Diminishes +14

Ring Finger Nuclear Factor RNF168 Is Important for Defects in Homologous Recombination Caused by Loss of the Breast Cancer Susceptibility Factor BRCA1

Meilen C. Muñoz, Corentin Laulier, Amanda Gunn, +4

Journal of Biological Chemistry

Chromosome length and gene density contribute to micronuclear membrane stability

Anna Mammel, Heather Z Huang, Amanda Gunn, +2

Life Science Alliance

GeneticsMolecular BiologyMolecular GeneticsCytoskeletonEpigenetics +14

A p62-dependent rheostat dictates micronuclei catastrophe and chromosome rearrangements

Sara Martin, Simone Scorzoni, Sara Cordone, +26

Science

Micronuclei CatastropheChromosomal InstabilityGeneticsMolecular BiologyCell Death +18