SEAM is a spatial single nuclear metabolomics method for dissecting tissue microenvironment

Zhiyuan Yuan, Qiming Zhou, Lesi Cai, +12

Nature Methods

Cell DivisionMolecular Biological MethodMedicineMolecular BiologyNuclear Organization +5

Vacuum Ultraviolet Laser Desorption/Ionization Mass Spectrometry Imaging of Single Cells with Submicron Craters

Jia Wang, Zhaoying Wang, Feng Liu, +7

Analytical Chemistry

EngineeringMicroscopyBiological Mass SpectrometryMolecular BiologySingle Cells +17

Chemical Visualization of Sweat Pores in Fingerprints Using GO-Enhanced TOF-SIMS

Lesi Cai, Meng-Chan Xia, Zhaoying Wang, +4

Analytical Chemistry

EngineeringMicroscopyBiometricsForensic ChemistryCrime Scene Trace +17

Cell-Penetrating Peptide Spirolactam Derivative as a Reversible Fluorescent pH Probe for Live Cell Imaging

Meng-Chan Xia, Lesi Cai, Sichun Zhang, +1

Analytical Chemistry

<i>In Situ</i> Identification and Spatial Mapping of Microplastic Standards in Paramecia by Secondary-Ion Mass Spectrometry Imaging

Jiaxin Feng, Hansen Zhao, Xiaoyun Gong, +9

Analytical Chemistry

A cell-penetrating ratiometric probe for simultaneous measurement of lysosomal and cytosolic pH change

Meng-Chan Xia, Lesi Cai, Sichun Zhang, +1

Talanta

BiochemistryMolecular Biological MethodMedicineNatural SciencesBioanalysis +9

Graphene Oxide as a Novel Evenly Continuous Phase Matrix for TOF-SIMS

Lesi Cai, Linfeng Sheng, Meng-Chan Xia, +4

Journal of the American Society for Mass Spectrometry

Simultaneous imaging of newly synthesized proteins and lipids in single cell by TOF-SIMS

Linfeng Sheng, Lesi Cai, Jia Wang, +6

International Journal of Mass Spectrometry

Proteinlipid InteractionBiochemistrySingle CellNatural SciencesNovel Imaging Method +8

Tuning the p<i>K</i>_a of Carboxyfluorescein with Arginine-Rich Cell-Penetrating Peptides for Intracellular pH Imaging

Meng-Chan Xia, Lesi Cai, Yan Yang, +2

Analytical Chemistry

Investigation into the content change and distribution of active components in Cordyceps sinensis with growth cycle by direct TOF-SIMS detection

Meng-Chan Xia, Qin Zhan, Lesi Cai, +5

Microchemical Journal

BiologyCordyceps SinensisPlant AnalysisDirect Tof-sims DetectionActive Components +9