Up-regulation of hypoxia-inducible factors HIF-1α and HIF-2α under normoxic conditions in renal carcinoma cells by von Hippel-Lindau tumor suppressor gene loss of function

Marion Krieg, Richard de Goeij-de Haas, Hiltrud Brauch, +3

Oncogene

Hypoxia-inducible Factors Hif-1αRedox RegulatorMedicineHypoxia (Medicine)Pathology +7

HRF, a putative basic helix-loop-helix-PAS-domain transcription factor is closely related to hypoxia-inducible factor-1α and developmentally expressed in blood vessels

Ingo Flamme, Thomas Fröhlich, Marie von Reutern, +3

Mechanisms of Development

Blood VesselsTranscriptional RegulationTranscription FactorsMolecular PhysiologyDevelopmental Biology +9

Expression and Proteolysis of Vascular Endothelial Growth Factor is Increased in Chronic Wounds

Gereon Lauer, Stephan Sollberg, Melanie Cole, +5

Journal of Investigative Dermatology

InflammationChronic WoundsEndothelial DysfunctionWound CareVascular Biology +6

Induction of vasculogenesis and hematopoiesis in vitro

Ingo Flamme, Werner Risau

Development

VasculitisImmunologyBlood CellEmbryologyAngiogenesis +15

Copper-dependent activation of hypoxia-inducible factor (HIF)-1: implications for ceruloplasmin regulation

Falk Martin, Tobias Linden, Dörthe M. Katschinski, +8

Blood

Flk-1 as a target for tumor growth inhibition.

L M Strawn, Gerald McMahon, Harald App, +15

PubMed

Endothelial CellsCancer BiologyTumor BiologyAngiogenesisReceptor Tyrosine Kinase +16

Vascular Endothelial Growth Factor (VEGF) and VEGF Receptor 2(flk-1) Are Expressed during Vasculogenesis and Vascular Differentiation in the Quail Embryo

Ingo Flamme, Georg Breier, Werner Risau

Developmental Biology

Developmental BiologyAngiogenesisVegf Receptor 2PhysiologyQuail Embryo +10

Cooperative Interaction of Hypoxia-inducible Factor-2α (HIF-2α) and Ets-1 in the Transcriptional Activation of Vascular Endothelial Growth Factor Receptor-2 (Flk-1)

Gerd Elvert, Andreas Kappel, Regina Heidenreich, +8

Journal of Biological Chemistry

Overexpression of Vascular Endothelial Growth Factor in the Avian Embryo Induces Hypervascularization and Increased Vascular Permeability without Alterations of Embryonic Pattern Formation

Ingo Flamme, Marie von Reutern, Hannes C. A. Drexler, +2

Developmental Biology

Animal PhysiologyVascular PermeabilityDevelopmental BiologyAngiogenesisVascular Adaptation +11

<scp>BAY</scp> 87‐2243, a highly potent and selective inhibitor of hypoxia‐induced gene activation has antitumor activities by inhibition of mitochondrial complex I

Peter Ellinghaus, Iring Heisler, Kerstin Unterschemmann, +11

Cancer Medicine

Cancer BiologyRedox BiologyTumor BiologyOxidative StressMolecular Pharmacology +19