Bacteriophage trigger antiviral immunity and prevent clearance of bacterial infection

Johanna M. Sweere, Jonas D. Van Belleghem, Heather D. Ishak, +18

Science

Hydrogel-based delivery of Il-10 improves treatment of bleomycin-induced lung fibrosis in mice

Elya A. Shamskhou, Michael J. Kratochvil, Mark Orcholski, +13

Biomaterials

InflammationCell-based Drug DeliveryTranslational MedicineFibrosisAntifibrotic Therapy +12

Inhibition of hyaluronan synthesis restores immune tolerance during autoimmune insulitis

Nadine Nagy, Gernot Kaber, Pamela Y. Johnson, +12

Journal of Clinical Investigation

InflammationType 1Treg DifferentiationImmune ToleranceAllergy +13

Pf4 bacteriophage produced by Pseudomonas aeruginosa inhibits Aspergillus fumigatus metabolism via iron sequestration

Jack C. Penner, Jose A. G. Ferreira, Patrick R. Secor, +13

Microbiology

Af BiofilmsPathogenic MicrobiologyBiochemistryBacteriologyBacteriophage +6

Engineered matrices reveal stiffness-mediated chemoresistance in patient-derived pancreatic cancer organoids

Bauer L. LeSavage, D.H. Zhang, Carla Huerta-López, +14

Nature Materials

EngineeringPancreatic CancerMedicineEngineered MatricesBiofabrication +9

Versican Deficiency Significantly Reduces Lung Inflammatory Response Induced by Polyinosine-Polycytidylic Acid Stimulation

Inkyung Kang, Ingrid A. Harten, Mary Y. Chang, +13

Journal of Biological Chemistry

Hyaluronan content governs tissue stiffness in pancreatic islet inflammation

Nadine Nagy, Adi de la Zerda, Gernot Kaber, +12

Journal of Biological Chemistry

4-Methylumbelliferyl glucuronide contributes to hyaluronan synthesis inhibition

Nadine Nagy, Irina Gurevich, Hedwich F. Kuipers, +11

Journal of Biological Chemistry

Medicinal ChemistryMedicineGlycobiologyMechanism Of ActionMatrix Biology +4

Phosphorylation of sterol regulatory element-binding protein (SREBP)-1c by p38 kinases, ERK and JNK influences lipid metabolism and the secretome of human liver cell line HepG2

Birgit Knebel, Stefan Lehr, Sonja Hartwig, +9

Archives of Physiology and Biochemistry

Fatty Liver DiseaseOxidative StressMetabolic SyndromeReceptor Tyrosine KinaseAutophagy +16

Cardiospecific Overexpression of the Prostaglandin EP ₃ Receptor Attenuates Ischemia-Induced Myocardial Injury

Melanie Martin, Jutta Meyer-Kirchrath, Gernot Kaber, +6

Circulation