Maintenance of neural progenitor cell stemness in 3D hydrogels requires matrix remodelling

Christopher M. Madl, Bauer L. LeSavage, Ruby E. Dewi, +8

Nature Materials

Tissue EngineeringRegenerative MedicineEngineeringMedicineAdult Stem Cell +11

Cancer-associated mesothelial cells promote ovarian cancer chemoresistance through paracrine osteopontin signaling

Jin Qian, Bauer L. LeSavage, Kelsea M. Hubka, +10

Journal of Clinical Investigation

Mesothelial CellsCancer BiologyTumor BiologyOvarian CancerSignaling Pathway +14

Matrix Remodeling Enhances the Differentiation Capacity of Neural Progenitor Cells in 3D Hydrogels

Christopher M. Madl, Bauer L. LeSavage, Ruby E. Dewi, +2

Advanced Science

Tissue EngineeringEngineeringDifferentiation CapacityBiofabricationCerebral Organoid +20

Tunable hydrogel viscoelasticity modulates human neural maturation

Julien G. Roth, Michelle S. Huang, Renato S. Navarro, +3

Science Advances

Tissue EngineeringNative Brain EcmEngineeringDevelopmental Cognitive NeuroscienceNeural Maturation +18

Engineered Matrices Enable the Culture of Human Patient‐Derived Intestinal Organoids

Daniel Hunt, Katarina C. Klett, Shamik Mascharak, +15

Advanced Science

Engineered matrices reveal stiffness-mediated chemoresistance in patient-derived pancreatic cancer organoids

Bauer L. LeSavage, D.H. Zhang, Carla Huerta-López, +14

Nature Materials

EngineeringPancreatic CancerMedicineEngineered MatricesBiofabrication +9

Bioprinting Cell- and Spheroid-Laden Protein-Engineered Hydrogels as Tissue-on-Chip Platforms

Daniela F. Duarte Campos, Christopher Lindsay, Julien G. Roth, +7

Frontiers in Bioengineering and Biotechnology

Bioprinting of stem cell expansion lattices

Christopher Lindsay, Julien G. Roth, Bauer L. LeSavage, +1

Acta Biomaterialia

Tissue EngineeringEngineeringMedicineAdult Stem CellBioprinting +7

Microrheology reveals simultaneous cell-mediated matrix stiffening and fluidization that underlie breast cancer invasion

Brad A. Krajina, Bauer L. LeSavage, Julien G. Roth, +4

Science Advances

EngineeringCell AdhesionBiological MicroenvironmentsBiofabricationCytoskeleton +19

Production of Elastin-like Protein Hydrogels for Encapsulation and Immunostaining of Cells in 3D

Bauer L. LeSavage, Nicholas A. Suhar, Christopher M. Madl, +1

Journal of Visualized Experiments

Tissue EngineeringCell EncapsulationEngineeringHydrogel Tissue CultureBiomaterials Design +18