Efficient Endoderm Induction from Human Pluripotent Stem Cells by Logically Directing Signals Controlling Lineage Bifurcations

Kyle M. Loh, Lay Teng Ang, Jingyao Zhang, +20

Cell stem cell

Regenerative MedicineEfficient Endoderm InductionInduced Pluripotent Stem CellDevelopmental BiologyMedicine +8

Forced aggregation of defined numbers of human embryonic stem cells into embryoid bodies fosters robust, reproducible hematopoietic differentiation

Elizabeth Ng, Richard P. Davis, Lisa Azzola, +2

Blood

Human definitive haemogenic endothelium and arterial vascular endothelium represent distinct lineages

Andrea Ditadi, Christopher M. Sturgeon, Joanna Tober, +12

Nature Cell Biology

Vascular DiseaseDevelopmental BiologyAngiogenesisCardiovascular DiseaseVascular Adaptation +9

Differentiation of human embryonic stem cells to HOXA+ hemogenic vasculature that resembles the aorta-gonad-mesonephros

Elizabeth S. Ng, Lisa Azzola, Freya Bruveris, +24

Nature Biotechnology

Embryonic Stem CellDevelopmental BiologyMedicineMorphogenesisStem Cell Research +6

A method for genetic modification of human embryonic stem cells using electroporation

Magdaline Costa, Mirella Dottori, Koula Sourris, +9

Nature Protocols

Induced Pluripotent Stem CellEngineeringGenetic ModificationGenetic EngineeringStem Cell Research +5

Differentiation of Human Embryonic Stem Cells in Serum-Free Medium Reveals Distinct Roles for Bone Morphogenetic Protein 4, Vascular Endothelial Growth Factor, Stem Cell Factor, and Fibroblast Growth Factor 2 in Hematopoiesis

Marjorie Pick, Lisa Azzola, Anna K. Mossman, +2

Stem Cells

Embryonic Stem CellDevelopmental BiologyDirected DifferentiationBone Morphogenic ProteinMedicine +10

The primitive streak gene<i>Mixl1</i>is required for efficient haematopoiesis and BMP4-induced ventral mesoderm patterning in differentiating ES cells

Elizabeth S. Ng, Lisa Azzola, Koula Sourris, +3

Development

GeneticsEfficient HaematopoiesisCell SpecializationPrimitive StreakEmbryology +15

Transcriptional profiling of mouse and human ES cells identifies SLAIN1, a novel stem cell gene

Claire E. Hirst, Elizabeth S. Ng, Lisa Azzola, +4

Developmental Biology

Transcriptional RegulationTranscriptional ProfilingDevelopmental BiologyCell LineageHuman Cell +7

Generation of Megakaryocytic Progenitors from Human Embryonic Stem Cells in a Feeder- and Serum-Free Medium

Marjorie Pick, Lisa Azzola, Elissa Osborne, +2

PLoS ONE

A protocol for removal of antibiotic resistance cassettes from human embryonic stem cells genetically modified by homologous recombination or transgenesis

Richard P. Davis, Magdaline Costa, Catarina Grandela, +8

Nature Protocols

Antimicrobial Resistance GeneHealth SciencesMedicineHomologous RecombinationStem Cell Engineering +10