David J. Porubek

17<i>β</i>-Estradiol 2- and 4-Hydroxylation Catalyzed by Rat Hepatic Cytochrome P-450: Roles of Individual Forms, Inductive Effects, Developmental Patterns, and Alterations by Gonadectomy and Hormone Replacement*

Ghazi A. Dannan, David J. Porubek, Sidney D. Nelson et al. · Endocrinology · 1986 · 131 citations

Life Sciences, Biochemistry, Endocrinology +17

Thiol-containing androgens as suicide substrates of aromatase

Patrick J. Bednarski, David J. Porubek, Sidney D. Nelson · Journal of Medicinal Chemistry · 1985 · 54 citations

Life Sciences, Biochemistry, Endocrinology +9

Quantitative metabolic profiling of valproic acid in humans using automated gas chromatographic/mass spectrometric techniques

Albert W. Rettenmeier, William N. Howald, René H. Levy et al. · Journal of Mass Spectrometry · 1989 · 49 citations

Life Sciences, Pharmaceutical Analysis, Pharmacology +17

On the role of calcium in the toxicity of alkylating and oxidizing quinone imines in isolated hepatocytes

Pierluigi Nicotera, Mats Rundgren, David J. Porubek et al. · Chemical Research in Toxicology · 1989 · 44 citations

Pharmacy, Biochemistry, Toxicology +13

Investigation of mechanisms of acetaminophen toxicity in isolated rat hepatocytes with the acetaminophen analogues 3,5-dimethylacetaminophen and 2,6-dimethylacetaminophen.

David J. Porubek, Mats Rundgren, Peter J. Harvison et al. · Molecular Pharmacology · 1987 · 40 citations

Pharmacy, Pharmacology, Toxicology +11