B cells are associated with survival and immunotherapy response in sarcoma

Florent Petitprez, Aurélien de Reyniès, Emily Z. Keung, +26

Nature

Tertiary lymphoid structures generate and propagate anti-tumor antibody-producing plasma cells in renal cell cancer

Maxime Meylan, Florent Petitprez, Étienne Becht, +20

Immunity

Lymphoid NeoplasiaGenitourinary CancerMalignant DiseaseMedicineImmunology +5

Mature tertiary lymphoid structures predict immune checkpoint inhibitor efficacy in solid tumors independently of PD-L1 expression

Lucile Vanhersecke, Maxime Brunet, Jean‐Philippe Guégan, +30

Nature Cancer

Lymphoid NeoplasiaCancer ImmunosurveillancePd-l1 ExpressionSolid TumorsMedicine +7

Pembrolizumab in soft-tissue sarcomas with tertiary lymphoid structures: a phase 2 PEMBROSARC trial cohort

Antoîne Italiano, Alban Bessede, M. Pulido, +17

Nature Medicine

Lymphoid NeoplasiaPembrosarc Trial CohortMedicineSoft-tissue SarcomasImmunology +5

Nivolumab, nivolumab–ipilimumab, and VEGFR-tyrosine kinase inhibitors as first-line treatment for metastatic clear-cell renal cell carcinoma (BIONIKK): a biomarker-driven, open-label, non-comparative, randomised, phase 2 trial

Yann Vano, Réza Elaidi, Mostefa Bennamoun, +39

The Lancet Oncology

UrologyOncologyGenitourinary CancerMedicineImmune Checkpoint Inhibitor +5

Identification, validation and biological characterisation of novel glioblastoma tumour microenvironment subtypes: implications for precision immunotherapy

Kirsten A. White, Kate Connor, Maxime Meylan, +42

Annals of Oncology

Early Hepatic Lesions Display Immature Tertiary Lymphoid Structures and Show Elevated Expression of Immune Inhibitory and Immunosuppressive Molecules

Maxime Meylan, Florent Petitprez, Laetitia Lacroix, +14

Clinical Cancer Research

Standardized Pathology Screening of Mature Tertiary Lymphoid Structures in Cancers

Lucile Vanhersecke, Antoine Bougoüin, Amandine Crombé, +17

Laboratory Investigation

Lymphoid NeoplasiaTumoral PathologyMedicineSurgical PathologyHistopathology +7

Complement C1s and C4d as Prognostic Biomarkers in Renal Cancer: Emergence of Noncanonical Functions of C1s

Marie V. Daugan, Margot Revel, Jules Russick, +22

Cancer Immunology Research

Baseline circulating unswitched memory B cells and B-cell related soluble factors are associated with overall survival in patients with clear cell renal cell carcinoma treated with nivolumab within the NIVOREN GETUG-AFU 26 study

Lucía Carril-Ajuria, Aude Desnoyer, Maxime Meylan, +20

Journal for ImmunoTherapy of Cancer