Anaerobic Glycolysis Maintains the Glomerular Filtration Barrier Independent of Mitochondrial Metabolism and Dynamics

Paul T. Brinkkoetter, Tillmann Bork, Sarah Salou, +19

Cell Reports

Cells grown in three-dimensional spheroids mirror in vivo metabolic response of epithelial cells

Simon Lagies, Manuel Schlimpert, Simon Neumann, +4

Communications Biology

Metabolic Adaptation during nab-Paclitaxel Resistance in Pancreatic Cancer Cell Lines

Lukas M. Braun, Simon Lagies, Jessica Guenzle, +3

Cells

Tumor BiologyPancreatic CancerMedicinePharmacologyMetabolic Adaptation +11

Cooperation between two periplasmic copper chaperones is required for full activity of the <i>cbb</i>₃‐type cytochrome <i>c</i> oxidase and copper homeostasis in <i>Rhodobacter capsulatus</i>

Petru‐Iulian Trasnea, Marcel Utz, Bahia Khalfaoui‐Hassani, +3

Molecular Microbiology

Molecular BiologyMicrobial PhysiologyChemical BiologyRedox BiologyCopper Homeostasis +14

A reciprocal regulation of spermidine and autophagy in podocytes maintains the filtration barrier

Wei Liang, Kosuke Yamahara, Camila Hernando-Erhard, +7

Kidney International

The Gb3-enriched CD59/flotillin plasma membrane domain regulates host cell invasion by Pseudomonas aeruginosa

Annette Brandel, Sahaja Aigal, Simon Lagies, +10

Cellular and Molecular Life Sciences

Enhanced AC133-specific CAR T cell therapy induces durable remissions in mice with metastatic small cell lung cancer

Sanaz Taromi, Elke Firat, Alexander Simonis, +19

Cancer Letters

Cancer ImmunosurveillanceMedicineImmunologyImmune Checkpoint InhibitorCancer Treatment +4

Metabolic profiling of isolated mitochondria and cytoplasm reveals compartment-specific metabolic responses

Daqiang Pan, Caroline Lindau, Simon Lagies, +2

Metabolomics

Novel lectin-based chimeric antigen receptors target Gb3-positive tumour cells

Ana Valeria Meléndez, Rubí M.-H. Velasco Cárdenas, Simon Lagies, +8

Cellular and Molecular Life Sciences

Metabolic rewiring tunes dermal macrophages in staphylococcal skin infection

Aaron James Forde, Julia Kolter, Pascale Zwicky, +15

Science Immunology