Distinctive binding properties of human monoclonal LGI1 autoantibodies determine pathogenic mechanisms

Melanie Ramberger, Antonio Berretta, Jeanne M.M. Tan, +22

Brain

A dominant mutation in <i>Snap25</i> causes impaired vesicle trafficking, sensorimotor gating, and ataxia in the blind-drunk mouse

Alexander Jeans, Peter L. Oliver, Reuben Johnson, +10

Proceedings of the National Academy of Sciences

GeneticsSynaptic TransmissionViable Mouse LineSynaptic SignalingCellular Physiology +18

A mutation in Af4 is predicted to cause cerebellar ataxia and cataracts in the robotic mouse.

Adrian M. Isaacs, Peter L. Oliver, Emma Jones, +11

PubMed

Knockout MouseDevelopmental BiologyOphthalmologyExperimental OphthalmologyRobotic Mouse +9

The epilepsy-associated protein TBC1D24 is required for normal development, survival and vesicle trafficking in mammalian neurons

Mattéa J. Finelli, Davide Aprile, Enrico Castroflorio, +13

Human Molecular Genetics

GeneticsTbc1d24 ExpressionTbc1d24 MutationsDisease Gene IdentificationCellular Neurobiology +22

A Mutation in<i>Af4</i>Is Predicted to Cause Cerebellar Ataxia and Cataracts in the Robotic Mouse

Adrian M. Isaacs, Peter L. Oliver, Emma Jones, +12

Journal of Neuroscience

Knockout MouseMolecular NeuroscienceDevelopmental BiologyOphthalmologyGenetics +12

Cell-Specific Loss of SNAP25 from Cortical Projection Neurons Allows Normal Development but Causes Subsequent Neurodegeneration

Anna Hoerder‐Suabedissen, Kim V. Korrell, S. Hayashi, +7

Cerebral Cortex

Synaptic TransmissionNeurodevelopmentNeurotransmissionCellular NeurobiologySocial Sciences +18

Hippocampal mGluR1-dependent long-term potentiation requires NAADP-mediated acidic store Ca ²⁺ signaling

William J. Foster, Henry B. C. Taylor, Zahid Padamsey, +2

Science Signaling

Identification of a New Pmp22 Mouse Mutant and Trafficking Analysis of a Pmp22 Allelic Series Suggesting That Protein Aggregates May Be Protective in Pmp22-Associated Peripheral Neuropathy

Adrian M. Isaacs, Alexander Jeans, Peter L. Oliver, +4

Molecular and Cellular Neuroscience

Trafficking AnalysisNeurodegenerative DiseasesMolecular NeuroscienceSignal TransductionImmunology +8

Long-term depression links amyloid-β to the pathological hyperphosphorylation of tau

Henry B. C. Taylor, Nigel J. Emptage, Alexander Jeans

Cell Reports

Homeostatic Presynaptic Plasticity Is Specifically Regulated by P/Q-type Ca2+ Channels at Mammalian Hippocampal Synapses

Alexander Jeans, Fran C. van Heusden, Bashayer Al‐Mubarak, +2

Cell Reports