Alexander Jeans

Distinctive binding properties of human monoclonal LGI1 autoantibodies determine pathogenic mechanisms

Melanie Ramberger, Antonio Berretta, Jeanne M.M. Tan et al. · Brain · 2020 · 123 citations · Full text

A dominant mutation in <i>Snap25</i> causes impaired vesicle trafficking, sensorimotor gating, and ataxia in the blind-drunk mouse

Alexander Jeans, Peter L. Oliver, Reuben Johnson et al. · Proceedings of the National Academy of Sciences · 2007 · 119 citations · Full text

Genetics, Synaptic Transmission, Viable Mouse Line +20

A mutation in Af4 is predicted to cause cerebellar ataxia and cataracts in the robotic mouse.

Adrian M. Isaacs, Peter L. Oliver, Emma Jones et al. · PubMed · 2003 · 72 citations · Full text

Knockout Mouse, Developmental Biology, Ophthalmology +11

The epilepsy-associated protein TBC1D24 is required for normal development, survival and vesicle trafficking in mammalian neurons

Mattéa J. Finelli, Davide Aprile, Enrico Castroflorio et al. · Human Molecular Genetics · 2018 · 64 citations · Full text

Genetics, Tbc1d24 Expression, Tbc1d24 Mutations +24

A Mutation in<i>Af4</i>Is Predicted to Cause Cerebellar Ataxia and Cataracts in the Robotic Mouse

Adrian M. Isaacs, Peter L. Oliver, Emma Jones et al. · Journal of Neuroscience · 2003 · 64 citations · Full text

Knockout Mouse, Molecular Neuroscience, Developmental Biology +14