Deborah Hagan

Discovery of Dapagliflozin: A Potent, Selective Renal Sodium-Dependent Glucose Cotransporter 2 (SGLT2) Inhibitor for the Treatment of Type 2 Diabetes

Wei Meng, Bruce A. Ellsworth, Alexandra A. Nirschl et al. · Journal of Medicinal Chemistry · 2008 · 612 citations · Full text

Metabolic Syndrome, Diabetes Management, Biochemistry +10

Dapagliflozin, a Selective SGLT2 Inhibitor, Improves Glucose Homeostasis in Normal and Diabetic Rats

Song‐Ping Han, Deborah Hagan, Joseph R. Taylor et al. · Diabetes · 2008 · 416 citations · Full text

Quantitative PCR tissue expression profiling of the human SGLT2 gene and related family members

Jian Chen, Sandy Williams, Samantha Ho et al. · Diabetes Therapy · 2010 · 300 citations · Full text

Mice mutant for glucokinase regulatory protein exhibit decreased liver glucokinase: A sequestration mechanism in metabolic regulation

Dennis Farrelly, Karen Brown, Aaron Tieman et al. · Proceedings of the National Academy of Sciences · 1999 · 152 citations · Full text

Liver Gk Activity, Glucose Homeostasis, Metabolic Remodeling +24

Transcriptional regulation of human and hamster microsomal triglyceride transfer protein genes. Cell type-specific expression and response to metabolic regulators.

Deborah Hagan, Bernadette Kienzle, H Jamil et al. · Journal of Biological Chemistry · 1994 · 125 citations · Full text

Transient Transfection Analysis, Transcriptional Regulation, Protein Expression +19