Robin R. Knight

Structural basis for the killing of human beta cells by CD8+ T cells in type 1 diabetes

Anna Bulek, David K. Cole, Ania Skowera et al. · Nature Immunology · 2012 · 178 citations

Type 1, Autoimmune Disease, Human Beta Cells +11

β-Cell–Specific CD8 T Cell Phenotype in Type 1 Diabetes Reflects Chronic Autoantigen Exposure

Ania Skowera, Kristin Ladell, James E. McLaren et al. · Diabetes · 2014 · 115 citations · Full text

Circulating Preproinsulin Signal Peptide–Specific CD8 T Cells Restricted by the Susceptibility Molecule HLA-A24 Are Expanded at Onset of Type 1 Diabetes and Kill β-Cells

Deborah Kronenberg‐Versteeg, Robin R. Knight, Megan Estorninho et al. · Diabetes · 2012 · 111 citations · Full text

Type 1, Autoimmune Disease, Diabetes +15

Clinical-Grade Multipotent Adult Progenitor Cells Durably Control Pathogenic T Cell Responses in Human Models of Transplantation and Autoimmunity

James L. Reading, Jennie H. M. Yang, Shereen Sabbah et al. · The Journal of Immunology · 2013 · 71 citations

Cell Therapy, T-regulatory Cell, Immunology +22

Human β-Cell Killing by Autoreactive Preproinsulin-Specific CD8 T Cells Is Predominantly Granule-Mediated With the Potency Dependent Upon T-Cell Receptor Avidity

Robin R. Knight, Deborah Kronenberg‐Versteeg, Min Zhao et al. · Diabetes · 2012 · 63 citations · Full text

Adaptive Immune System, T-regulatory Cell, Immune Regulation +26