Yoko Ogawara

Akt Enhances Mdm2-mediated Ubiquitination and Degradation of p53

Yoko Ogawara, Shohei Kishishita, Toshiyuki Obata et al. · Journal of Biological Chemistry · 2002 · 611 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

Selective inhibition of mutant IDH1 by DS-1001b ameliorates aberrant histone modifications and impairs tumor activity in chondrosarcoma

Makoto Nakagawa, Fumihiko Nakatani, Hironori Matsunaga et al. · Oncogene · 2019 · 69 citations · Full text

Medicine, Oncology, Pharmacology +14

IDH2 and NPM1 Mutations Cooperate to Activate Hoxa9/Meis1 and Hypoxia Pathways in Acute Myeloid Leukemia

Yoko Ogawara, Takuo Katsumoto, Yukiko Aikawa et al. · Cancer Research · 2015 · 58 citations

Medicine, Cancer Biology, Molecular Biology +15

A Potent Blood–Brain Barrier-Permeable Mutant IDH1 Inhibitor Suppresses the Growth of Glioblastoma with IDH1 Mutation in a Patient-Derived Orthotopic Xenograft Model

Yukino Machida, Makoto Nakagawa, Hironori Matsunaga et al. · Molecular Cancer Therapeutics · 2019 · 55 citations · Full text

Medicine, Oncology, Pharmacology +15

Dual inhibition of enhancer of zeste homolog 1/2 overactivates <scp>WNT</scp> signaling to deplete cancer stem cells in multiple myeloma

Makoto Nakagawa, Shuhei Fujita, Takuo Katsumoto et al. · Cancer Science · 2018 · 25 citations · Full text

Medicine, Oncology, Pharmacology +17