Concepedia

Author

Duncan Sproul

Institute of Genetics and CancerORCID

Also Known As

D Sproul, D. Sproul, Duncan Sproul, Sproul D, Sproul, Duncan, the PHOSP-COVID Study Collaborative Group

89

Publications

4.9K

Citations

29

H-Index

38

Concepts

All Affiliations

Institute of Genetics and CancerUniversity of EdinburghEdinburgh Cancer ResearchWestern General HospitalMedical Research Council
DS

About

Duncan Sproul is an author at Institute of Genetics and Cancer specializing in medicine, cell biology, and gene expression.

Top Concepts

#ConceptH-IndexPublicationsCitations

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Medicine

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Cell Biology

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Natural Sciences

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Molecular Biology

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Immunology

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258

Duncan Sproul

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33

Publications

4.3K

Citations

26

H-Index

YearCitations

Recruitment to the Nuclear Periphery Can Alter Expression of Genes in Human Cells

Lee Finlan, Duncan Sproul, Inga Thomson,

PLoS Genetics

2008

568

Ring1B Compacts Chromatin Structure and Represses Gene Expression Independent of Histone Ubiquitination

Ragnhild Eskeland, Martin Leeb, Graeme R. Grimes,

Molecular Cell

2010

538

Tissue type is a major modifier of the 5-hydroxymethylcytosine content of human genes

Colm E. Nestor, Raffaele Ottaviano, James P. Reddington,

Genome Research

2011

404

Glioblastomas acquire myeloid-affiliated transcriptional programs via epigenetic immunoediting to elicit immune evasion

Ester Gangoso, Benjamin Southgate, Leanne Bradley,

Cell

2021

335

Lactate, a product of glycolytic metabolism, inhibits histone deacetylase activity and promotes changes in gene expression

Tom Latham, C. Logan Mackay, Duncan Sproul,

Nucleic Acids Research

2012

324

Tissue of origin determines cancer-associated CpG island promoter hypermethylation patterns

Duncan Sproul, Robert R. Kitchen, Colm E. Nestor,

Genome biology

2012

199

Diverse interventions that extend mouse lifespan suppress shared age-associated epigenetic changes at critical gene regulatory regions

John Cole, Neil Robertson, Mohammed Rather,

Genome biology

2017

196

cGAS-mediated induction of type I interferon due to inborn errors of histone pre-mRNA processing

Carolina Uggenti, Alice Lepelley, Marine Depp,

Nature Genetics

2020

185

Transcriptionally repressed genes become aberrantly methylated and distinguish tumors of different lineages in breast cancer

Duncan Sproul, Colm E. Nestor, Jayne Culley,

Proceedings of the National Academy of Sciences

2011

176

Gain-of-function DNMT3A mutations cause microcephalic dwarfism and hypermethylation of Polycomb-regulated regions

Patricia Heyn, Clare V. Logan, Adeline Fluteau,

Nature Genetics

2018

151

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