Guowen Ren

Cucurbitacin B induces DNA damage and autophagy mediated by reactive oxygen species (ROS) in MCF-7 breast cancer cells

Guowen Ren, Tongye Sha, Jiajie Guo et al. · Journal of Natural Medicines · 2015 · 63 citations

Tumor Biology, Dna Damage, Reactive Oxygen Species +10

Psoralidin induced reactive oxygen species (ROS)-dependent DNA damage and protective autophagy mediated by NOX4 in breast cancer cells

Guowen Ren, Weiwei Luo, Wen Sun et al. · Phytomedicine · 2016 · 53 citations

Cell Autophagy, Mitophagy, Medicine +10

Bromodomain and extra-terminal motif (BET) inhibition is synthetic lethal with loss of SMAD4 in colorectal cancer cells via restoring the loss of MYC repression

Changxiang Shi, Eun Ju Yang, Yifan Liu et al. · Oncogene · 2020 · 45 citations

Myc Repression, Cancer Research, Cell Regulation +9

Cucurbitacin B Induces DNA Damage, G2/M Phase Arrest, and Apoptosis Mediated by Reactive Oxygen Species (ROS) in Leukemia K562 Cells

Jiajie Guo, Wenwen Zhao, Wenhui Hao et al. · Anti-Cancer Agents in Medicinal Chemistry · 2014 · 41 citations

Aurora kinase A inhibition induces synthetic lethality in SMAD4-deficient colorectal cancer cells via spindle assembly checkpoint activation

Changxiang Shi, Shishi Tao, Guowen Ren et al. · Oncogene · 2022 · 16 citations

Cell Regulation, Receptor Tyrosine Kinase, Synthetic Lethality +8