Dakota B. Poschel

Tumor PD-L1 engages myeloid PD-1 to suppress type I interferon to impair cytotoxic T lymphocyte recruitment

John D. Klement, Priscilla S. Redd, Chunwan Lu et al. · Cancer Cell · 2023 · 111 citations · Full text

Immunology, Pathology, Immunotherapy +18

Asah2 Represses the p53–Hmox1 Axis to Protect Myeloid-Derived Suppressor Cells from Ferroptosis

Huabin Zhu, John D. Klement, Chunwan Lu et al. · The Journal of Immunology · 2021 · 107 citations · Full text

WDR5-H3K4me3 epigenetic axis regulates OPN expression to compensate PD-L1 function to promote pancreatic cancer immune escape

Chunwan Lu, Zhuoqi Liu, John D. Klement et al. · Journal for ImmunoTherapy of Cancer · 2021 · 106 citations · Full text

Osteopontin Blockade Immunotherapy Increases Cytotoxic T Lymphocyte Lytic Activity and Suppresses Colon Tumor Progression

John D. Klement, Dakota B. Poschel, Chunwan Lu et al. · Cancers · 2021 · 49 citations · Full text

Cancer Immunosurveillance, Opn Protein Level, Opn Blockade Immunotherapy +12

Lipid Nanoparticle Delivery of Fas Plasmid Restores Fas Expression to Suppress Melanoma Growth <i>In Vivo</i>

Zeinab Y. Al Subeh, Dakota B. Poschel, Priscilla S. Redd et al. · ACS Nano · 2022 · 33 citations · Full text