Transplantation of Genetically Corrected Human iPSC-Derived Progenitors in Mice with Limb-Girdle Muscular Dystrophy

Francesco Saverio Tedesco, M Gerli, Laura Perani, +21

Science Translational Medicine

Complete Genetic Correction of iPS Cells From Duchenne Muscular Dystrophy

Yasuhiro Kazuki, Masaharu Hiratsuka, Masato Takiguchi, +13

Molecular Therapy

Stem Cell–Mediated Transfer of a Human Artificial Chromosome Ameliorates Muscular Dystrophy

Francesco Saverio Tedesco, Hidetoshi Hoshiya, Giuseppe D’Antona, +11

Science Translational Medicine

Refined human artificial chromosome vectors for gene therapy and animal transgenesis

Yasuhiro Kazuki, Hidetoshi Hoshiya, Masafumi Takiguchi, +20

Gene Therapy

Gene TherapiesAnimal TransgenesisDevelopmental BiologyTransgenic Mouse ModelsGenetics +7

A highly Stable and Nonintegrated Human Artificial Chromosome (HAC) Containing the 2.4 Mb Entire Human Dystrophin Gene

Hidetoshi Hoshiya, Yasuhiro Kazuki, Satoshi Abe, +9

Molecular Therapy

CytogeneticsGeneticsMolecular GeneticsEpigeneticsGenetic Medicine +20

Frequent loss of imprinting of <i>IGF2</i> and <i>MEST</i> in lung adenocarcinoma

Masakazu Kohda, Hidetoshi Hoshiya, Motonobu Katoh, +5

Molecular Carcinogenesis

GeneticsLung AdenocarcinomaPathologyEpigeneticsTumor Biology +20

A new imprinted cluster on the human chromosome 7q21-q31, identified by human-mouse monochromosomal hybrids

Chiga Okita, Makiko Meguro, Hidetoshi Hoshiya, +3

Genomics

ChromatinEpigenetic ChangeGeneticsMolecular BiologyChromosome Biology +9

Trans-chromosomic mice containing a human CYP3A cluster for prediction of xenobiotic metabolism in humans

Yasuhiro Kazuki, Kaoru Kobayashi, Sasitorn Aueviriyavit, +16

Human Molecular Genetics

CytogeneticsGeneticsHuman Cyp3aGene CharacterizationMolecular Genetics +19

Human Artificial Chromosome with a Conditional Centromere for Gene Delivery and Gene Expression

Yuichi Iida, Jung‐Hyun Kim, Yasuhiro Kazuki, +10

DNA Research

A Novel Human Artificial Chromosome Vector Provides Effective Cell Lineage–Specific Transgene Expression in Human Mesenchymal Stem Cells

Xianying Ren, Motonobu Katoh, Hidetoshi Hoshiya, +6

Stem Cells

Regenerative MedicineMesenchymal Stem CellsGene TherapiesInduced Pluripotent Stem CellDevelopmental Biology +13