Georges Orfanoudakis

Structural and Functional Analysis of E6 Oncoprotein: Insights in the Molecular Pathways of Human Papillomavirus-Mediated Pathogenesis

Yves Nominé, Murielle Masson, Sébastian Charbonnier et al. · Molecular Cell · 2006 · 176 citations · Full text

Virus Structure, Molecular Biology, Virology +11

Sites of disruption within E1 and E2 genes of HPV16 and association with cervical dysplasia

D. Tsakogiannis, P. Gortsilas, Zaharoula Kyriakopoulou et al. · Journal of Medical Virology · 2015 · 53 citations

Precancerous Lesions, Genetics, Pathology +16

Proteasomal Degradation of p53 by Human Papillomavirus E6 Oncoprotein Relies on the Structural Integrity of p53 Core Domain

Xavier Bernard, Philip Robinson, Yves Nominé et al. · PLoS ONE · 2011 · 52 citations · Full text

Viral E6, Molecular Biology, Pathology +16

Surface plasmon resonance analysis of the binding of high‐risk mucosal HPV E6 oncoproteins to the PDZ1 domain of the tight junction protein MAGI‐1

Sadek Fournane, Sébastian Charbonnier, Anne Chapelle et al. · Journal of Molecular Recognition · 2010 · 37 citations

A single-codon mutation converts HPV16 E6 oncoprotein into a potential tumor suppressor, which induces p53-dependent senescence of HPV-positive HeLa cervical cancer cells

Tutik Ristriani, Sadek Fournane, Georges Orfanoudakis et al. · Oncogene · 2008 · 33 citations

Cervical Cancer, Oncogenic Agent, P53-dependent Senescence +9