Masuo Inoue

Antineoplastic agents. 147. Isolation and structure of the powerful cell growth inhibitor cephalostatin 1

George R. Pettit, Masuo Inoue, Yoshiaki Kamano et al. · Journal of the American Chemical Society · 1988 · 181 citations

Medicinal Chemistry, Pharmaceutical Science, Donut Icon +14

Structure–cytotoxic activity relationship for the toad poison bufadienolides

Yoshiaki Kamano, Ayano Kotake, Hirofumi Hashima et al. · Bioorganic & Medicinal Chemistry · 1998 · 126 citations

Biochemistry, Medicine, Structure–cytotoxic Activity Relationship +3

Marine Animal Biosynthetic Constituents For Cancer Chemotherapy

George R. Pettit, Yoshiaki Kamano, Youichi Fujii et al. · Journal of Natural Products · 1981 · 84 citations

Medicinal Chemistry, Marine Biotechnology, Oncogenic Agent +13

Antineoplastic agents. 3. Structure of the cyclic peptide dolastatin 3 from Dolabella auricularia

George R. Pettit, Yoshiaki Kamano, Peter Brown et al. · Journal of the American Chemical Society · 1982 · 77 citations

Pharmaceutical Science, Altmetric Attention Score, Peptide Science +18

Cephalostatin 1 selectively triggers the release of Smac/DIABLO and subsequent apoptosis that is characterized by an increased density of the mitochondrial matrix.

Verena M. Dirsch, Irina M. Müller, Sören T. Eichhorst et al. · PubMed · 2003 · 68 citations

Inflammation, Mitophagy, Cephalostatin 1-Induced Apoptosis +15