Paul Smith

DRAM, a p53-Induced Modulator of Autophagy, Is Critical for Apoptosis

Diane Crighton, Simon Wilkinson, Jim O’Prey et al. · Cell · 2006 · 1.3K citations · Full text

Cell Autophagy, Mitophagy, Apoptosis +8

p53 mutation with frequent novel codons but not a mutator phenotype in BRCA1- and BRCA2-associated breast tumours

Tim Crook, Louise Brooks, Susan Crossland et al. · Oncogene · 1998 · 178 citations

Brca2-associated Breast Tumours, Oncology, Somatic Variant +12

Arylamine N-acetyltransferase-1 is highly expressed in breast cancers and conveys enhanced growth and resistance to etoposide in vitro.

Paul J. Adam, Joanne Berry, Julie Loader et al. · PubMed · 2003 · 115 citations

Breast Oncology, Arylamine N-acetyltransferase-1, Breast Cancer Tissues +17

Novel p53 mutants selected in BRCA-associated tumours which dissociate transformation suppression from other wild-type p53 functions

Paul Smith, Susan Crossland, Gillian A. Parker et al. · Oncogene · 1999 · 107 citations

Brca-associated Tumours, Transformation Suppression, Novel P53 Mutants +8

Epigenetic downregulation of human disabled homolog 2 switches TGF-β from a tumor suppressor to a tumor promoter

Adèle Hannigan, Paul Smith, Gabriela Kalna et al. · Journal of Clinical Investigation · 2010 · 101 citations · Full text