Systematic Analysis of Diguanylate Cyclases That Promote Biofilm Formation by Pseudomonas fluorescens Pf0-1

Peter D. Newell, Shiro Yoshioka, Kelli L. Hvorecny, +2

Journal of Bacteriology

BiofilmsBiofilm FormationDistinct DgcsMedicineVirulence Factor +9

<i>Pseudomonas aeruginosa</i>sabotages the generation of host proresolving lipid mediators

Becca A. Flitter, Kelli L. Hvorecny, Emiko Ono, +13

Proceedings of the National Academy of Sciences

Lysogenic host–virus interactions in SAR11 marine bacteria

Robert M. Morris, Kelsy Cain, Kelli L. Hvorecny, +1

Nature Microbiology

Virus StructureSar11 Marine BacteriaVirologyMicrobiologyMicrobial Virus +2

Human PRPS1 filaments stabilize allosteric sites to regulate activity

Kelli L. Hvorecny, Kenzee Hargett, Joel Quispe, +1

Nature Structural & Molecular Biology

Protein FunctionSignal TransductionCell SignalingCytoskeletonCellular Biochemistry +4

Sequence variation in the β7–β8 loop of bacterial class A sortase enzymes alters substrate selectivity

Isabel M. Piper, Sarah A. Struyvenberg, Jordan D. Valgardson, +8

Journal of Biological Chemistry

Substrate SelectivityMolecular BiologyAnalytical UltracentrifugationBacterial PathogensStructure-function Enzyme Kinetics +15

An epoxide hydrolase secreted by<i>Pseudomonas aeruginosa</i>decreases mucociliary transport and hinders bacterial clearance from the lung

Kelli L. Hvorecny, Emily F. Dolben, Sophie Moreau‐Marquis, +9

American Journal of Physiology-Lung Cellular and Molecular Physiology

Rational Design of Potent and Selective Inhibitors of an Epoxide Hydrolase Virulence Factor from <i>Pseudomonas aeruginosa</i>

Seiya Kitamura, Kelli L. Hvorecny, Jun Niu, +3

Journal of Medicinal Chemistry

Selective InhibitorsCif Active SiteChemical BiologyBacterial PathogensMedicinal Chemistry +17

Signature Motifs Identify an Acinetobacter Cif Virulence Factor with Epoxide Hydrolase Activity

Christopher D. Bahl, Kelli L. Hvorecny, Andrew A. Bridges, +5

Journal of Biological Chemistry

Signature Motifs IdentifyMedical MicrobiologyMolecular PhysiologyBiochemistryEpoxide Hydrolase +11

Active-Site Flexibility and Substrate Specificity in a Bacterial Virulence Factor: Crystallographic Snapshots of an Epoxide Hydrolase

Kelli L. Hvorecny, Christopher D. Bahl, Seiya Kitamura, +4

Structure

Active-site FlexibilityBiochemistryEpoxide HydrolaseNatural SciencesVirulence Factor +8

Nanobody-based binding assay for the discovery of potent inhibitors of CFTR inhibitory factor (Cif)

Natalia Vasylieva, Seiya Kitamura, Jie-Xian Dong, +7

Analytica Chimica Acta

NanomedicineDrug TargetBiochemistryMedicinePharmacology +7