Isabel M. Piper

Sequence variation in the β7–β8 loop of bacterial class A sortase enzymes alters substrate selectivity

Isabel M. Piper, Sarah A. Struyvenberg, Jordan D. Valgardson et al. · Journal of Biological Chemistry · 2021 · 27 citations · Full text

Life Sciences, Biochemistry, Microbiology +17

Structures of Streptococcus pyogenes class A sortase in complex with substrate and product mimics provide key details of target recognition

D. Alex Johnson, Isabel M. Piper, Brandon A. Vogel et al. · Journal of Biological Chemistry · 2022 · 23 citations · Full text

Life Sciences, Biochemistry, Microbiology +12

Structural and biochemical analyses of selectivity determinants in chimeric <i>Streptococcus</i> Class A sortase enzymes

Melody Gao, D. Alex Johnson, Isabel M. Piper et al. · Protein Science · 2021 · 21 citations · Full text

Life Sciences, Microbiology, Molecular Biology +16

Comparative Analysis and Ancestral Sequence Reconstruction of Bacterial Sortase Family Proteins Generates Functional Ancestral Mutants with Different Sequence Specificities

Jordan D. Valgardson, Sarah A. Struyvenberg, Zachary R. Sailer et al. · Bacteria · 2022 · 11 citations · Full text

Life Sciences, Bioinformatics, Microbiology +17