D. Alex Johnson

Sequence variation in the β7–β8 loop of bacterial class A sortase enzymes alters substrate selectivity

Isabel M. Piper, Sarah A. Struyvenberg, Jordan D. Valgardson et al. · Journal of Biological Chemistry · 2021 · 24 citations · Full text

Substrate Selectivity, Molecular Biology, Analytical Ultracentrifugation +17

Structures of Streptococcus pyogenes class A sortase in complex with substrate and product mimics provide key details of target recognition

D. Alex Johnson, Isabel M. Piper, Brandon A. Vogel et al. · Journal of Biological Chemistry · 2022 · 20 citations · Full text

Structural and biochemical analyses of selectivity determinants in chimeric <i>Streptococcus</i> Class A sortase enzymes

Melody Gao, D. Alex Johnson, Isabel M. Piper et al. · Protein Science · 2021 · 18 citations · Full text

Protein Assembly, Bacteriology, Individual Srta Sequence +16

Comparative Analysis and Ancestral Sequence Reconstruction of Bacterial Sortase Family Proteins Generates Functional Ancestral Mutants with Different Sequence Specificities

Jordan D. Valgardson, Sarah A. Struyvenberg, Zachary R. Sailer et al. · Bacteria · 2022 · 10 citations · Full text