Shengqi He

The metabolic ER stress sensor IRE1α suppresses alternative activation of macrophages and impairs energy expenditure in obesity

Bo Shan, Xiaoxia Wang, Ying Wu et al. · Nature Immunology · 2017 · 362 citations

Inflammation, Obesity, Metabolic Syndrome +14

IL-27 signalling promotes adipocyte thermogenesis and energy expenditure

Qian Wang, Dehai Li, Guangchao Cao et al. · Nature · 2021 · 176 citations

Obesity, Energy Homeostasis, Medicine +6

Antimalarial artesunate protects sepsis model mice against heat-killed Escherichia coli challenge by decreasing TLR4, TLR9 mRNA expressions and transcription factor NF-κB activation

Bin Li, Rong Zhang, Jun Li et al. · International Immunopharmacology · 2008 · 75 citations

Microbial Pathogens, Innate Immune System, Immunology +17

Adipocyte IRE1α promotes PGC1α mRNA decay and restrains adaptive thermogenesis

Yong Chen, Zhuyin Wu, Shijia Huang et al. · Nature Metabolism · 2022 · 55 citations

Energy Homeostasis, Transcriptional Regulation, Physiology +10

IRE1α regulates skeletal muscle regeneration through myostatin mRNA decay

Shengqi He, Tingting Fu, Yue Yu et al. · Journal of Clinical Investigation · 2021 · 51 citations · Full text

Muscle Function, Molecular Regulation, Cellular Physiology +18