Chu Kwen Ho

ATR inhibition disrupts rewired homologous recombination and fork protection pathways in PARP inhibitor-resistant BRCA-deficient cancer cells

Stephanie A. Yazinski, Valentine Comaills, Rémi Buisson et al. · Genes & Development · 2017 · 386 citations · Full text

Replication Fork Protection, Genome Instability, Health Sciences +15

Coupling of Homologous Recombination and the Checkpoint by ATR

Rémi Buisson, Niraj Joshi, Amélie Rodrigue et al. · Molecular Cell · 2017 · 178 citations · Full text

Genome Instability, Homologous Recombination, Molecular Biology +4

Mus81 and Yen1 Promote Reciprocal Exchange during Mitotic Recombination to Maintain Genome Integrity in Budding Yeast

Chu Kwen Ho, Gerard Mazón, Alicia Lam et al. · Molecular Cell · 2010 · 166 citations · Full text

Budding Yeast, Mitotic Recombination, Cell Division +9

Nek1 kinase associates with ATR–ATRIP and primes ATR for efficient DNA damage signaling

Shizhou Liu, Chu Kwen Ho, Jian Ouyang et al. · Proceedings of the National Academy of Sciences · 2013 · 73 citations · Full text

The Rad1-Rad10 nuclease promotes chromosome translocations between dispersed repeats

Gerard Mazón, Alicia Lam, Chu Kwen Ho et al. · Nature Structural & Molecular Biology · 2012 · 45 citations · Full text

Chromatin, Genome Instability, Genetics +5