Reza Kiarash

Carnitine palmitoyltransferase 1C promotes cell survival and tumor growth under conditions of metabolic stress

Kathrin Zaugg, Yi Yao, Patrick T. Reilly et al. · Genes & Development · 2011 · 498 citations · Full text

Life Sciences, Biochemistry, Oncology +17

Functional Characterization of CFI-400945, a Polo-like Kinase 4 Inhibitor, as a Potential Anticancer Agent

Jacqueline M. Mason, Dan Lin, Yi Che et al. · Cancer Cell · 2014 · 200 citations · Full text

Medicine, Medicinal Chemistry, Oncology +15

The Discovery of Polo-Like Kinase 4 Inhibitors: Identification of (1<i>R</i>,2<i>S</i>)-2-(3-((<i>E</i>)-4-(((<i>cis</i>)-2,6-Dimethylmorpholino)methyl)styryl)-1<i>H</i>-indazol-6-yl)-5′-methoxyspiro[cyclopropane-1,3′-indolin]-2′-one (CFI-400945) as a Potent, Orally Active Antitumor Agent

Peter B. Sampson, Yong Liu, Bryan Forrest et al. · Journal of Medicinal Chemistry · 2014 · 171 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +10

Functional characterization of CFI-402257, a potent and selective Mps1/TTK kinase inhibitor, for the treatment of cancer

Jacqueline M. Mason, Graham C. Fletcher, Reza Kiarash et al. · Proceedings of the National Academy of Sciences · 2017 · 136 citations · Full text

Medicine, Oncology, Pharmacology +17

111In-labeled EGF is selectively radiotoxic to human breast cancer cells overexpressing EGFR.

Reza Kiarash, Ross Cameron, Nicole Porlier et al. · PubMed · 2000 · 135 citations

Medicine, Oncology, Pharmacology +17