Design of fast proteolysis-based signaling and logic circuits in mammalian cells

Tina Fink, Jan Lonzarić, Arne Praznik, +9

Nature Chemical Biology

Molecular PhysiologySignal TransductionCell EngineeringMammalian CellsMedicine +12

Design of coiled-coil protein-origami cages that self-assemble in vitro and in vivo

Ajasja Ljubetič, Fabio Lapenta, Helena Gradišar, +14

Nature Biotechnology

Tissue EngineeringEngineeringCoiled-coil Drug DeliveryProtein FoldingSelf-assembly +9

Self-assembly and regulation of protein cages from pre-organised coiled-coil modules

Fabio Lapenta, Jana Aupič, Marco Vezzoli, +6

Nature Communications

MicroRNA Silencing by DNA Methylation in Human Cancer: a Literature Analysis

Žiga Strmšek, Tanja Kunej

Non-Coding RNA

Histone ModificationsEngineeringEpigenetic ChangeGeneticsDna Methylation +18

A Nanoscaffolded Spike-RBD Vaccine Provides Protection against SARS-CoV-2 with Minimal Anti-Scaffold Response

Duško Lainšček, Tina Fink, Vida Forstnerič, +25

Vaccines

Rbd DomainEngineeringImmunologyImmunodominanceImmunotherapeutics +20

Metal ion–regulated assembly of designed modular protein cages

Jana Aupič, Fabio Lapenta, Žiga Strmšek, +3

Science Advances

Supramolecular AssemblyCc SetCc HeterodimersProtein AssemblyPeptide Engineering +14

Selective inhibition of NLRP3 inflammasome by designed peptide originating from ASC

Petra Sušjan, Duško Lainšček, Žiga Strmšek, +3

The FASEB Journal

Peptide EngineeringImmunologyCell DeathNeuroinflammationInflammation +21

Designed folding pathway of modular coiled-coil-based proteins

Jana Aupič, Žiga Strmšek, Fabio Lapenta, +5

Nature Communications

A nanobody toolbox targeting dimeric coiled-coil modules for functionalization of designed protein origami structures

Andreja Majerle, San Hadži, Jana Aupič, +6

Proceedings of the National Academy of Sciences

Design of split superantigen fusion proteins for cancer immunotherapy

Anja Golob-Urbanc, Uroš Rajčević, Žiga Strmšek, +1

Journal of Biological Chemistry

Cancer ImmunosurveillanceT CellsTarget CellsImmunologyTumor Immunity +12