Design of coiled-coil protein-origami cages that self-assemble in vitro and in vivo

Ajasja Ljubetič, Fabio Lapenta, Helena Gradišar, +14

Nature Biotechnology

Tissue EngineeringEngineeringCoiled-coil Drug DeliveryProtein FoldingSelf-assembly +9

A tunable orthogonal coiled-coil interaction toolbox for engineering mammalian cells

Tina Lebar, Duško Lainšček, Estera Merljak, +2

Nature Chemical Biology

EngineeringCoiled-coil Drug DeliveryMedicineBioelectronicsSynthetic Biology +11

Self-assembly and regulation of protein cages from pre-organised coiled-coil modules

Fabio Lapenta, Jana Aupič, Marco Vezzoli, +6

Nature Communications

Exploring the Anticancer Activity of Tamoxifen-Based Metal Complexes Targeting Mitochondria

Valeria Scalcon, Riccardo Bonsignore, Jana Aupič, +7

Journal of Medicinal Chemistry

Coiled-coil heterodimers with increased stability for cellular regulation and sensing SARS-CoV-2 spike protein-mediated cell fusion

Tjaša Plaper, Jana Aupič, Petra Dekleva, +4

Scientific Reports

A Nanoscaffolded Spike-RBD Vaccine Provides Protection against SARS-CoV-2 with Minimal Anti-Scaffold Response

Duško Lainšček, Tina Fink, Vida Forstnerič, +25

Vaccines

Rbd DomainEngineeringImmunologyImmunodominanceImmunotherapeutics +20

Metal ion–regulated assembly of designed modular protein cages

Jana Aupič, Fabio Lapenta, Žiga Strmšek, +3

Science Advances

Supramolecular AssemblyCc SetCc HeterodimersProtein AssemblyPeptide Engineering +14

SwitCCh: Metal‐Site Design for Controlling the Assembly of a Coiled‐Coil Homodimer

Jana Aupič, Fabio Lapenta, Roman Jerala

ChemBioChem

Topology of Folded Molecular Chains: From Single Biomolecules to Engineered Origami

Barbara Scalvini, Vahid Sheikhhassani, Jaie Woodard, +4

Trends in Chemistry

Dna NanotechnologyEngineered OrigamiEngineeringFolded Molecular ChainsProtein Folding +11

Dynamical interplay between the human high-affinity copper transporter hCtr1 and its cognate metal ion

Gulshan R. Walke, Jana Aupič, Hadeel Kashoua, +7

Biophysical Journal

Cognate Metal IonMolecular BiologyDynamical InterplayChemistryAnalytical Ultracentrifugation +17